Arizona Diamondbacks vs St. Louis Cardinals MLB Betting Prediction

MLB Arizona vs St. Louis Cardinals Prediction 5/23

The Arizona Diamondbacks will play against the St. Louis Cardinals on Friday, May 23, 2025. The game will take place at Busch Stadium and is scheduled for 8:15 PM. This night game will see the Diamondbacks as the away team and the Cardinals at home.

Diamondbacks vs. Cardinals Betting Prediction

  • Money Line Prediction: Cardinals MoneyLine: 110. The Cardinals have a slightly better record and a strong home performance. Their pitching stats are better, with a lower ERA and WHIP compared to the Diamondbacks.
  • Over/Under Prediction: Under 8.5 (-106). Both starting pitchers have shown inconsistency, but the Cardinals’ pitching staff has a better ERA and fewer home runs allowed, suggesting a lower-scoring game.

Team Trends

  • The Arizona Diamondbacks have a division record of 7-6 and are 5 games back in the NL West.
  • The St. Louis Cardinals hold a division record of 8-5 and are 3 games back in the NL Central.
  • In a recent spring training game, Arizona’s Corbin Burnes pitched 7 innings with 8 strikeouts against the Los Angeles Dodgers.
  • Arizona’s Ketel Marte hit a home run in a 1-0 win against the Colorado Rockies on May 18th, 2025.
  • St. Louis Cardinals’ Alec Burleson hit a home run in a 2-1 loss to the Kansas City Royals on May 18th, 2025.

Diamondbacks vs Cardinals Preview

The Arizona Diamondbacks are set to take on the St. Louis Cardinals at Busch Stadium on Friday, May 23, 2025. The game will begin at 8:15 PM, with the Diamondbacks playing as the away team. Zac Gallen will start on the mound for Arizona. He has made ten starts this season, posting a 3-5 record with an ERA of 5.14. Gallen will aim to improve his performance against the Cardinals.

For the Cardinals, Miles Mikolas will be the starting pitcher. Mikolas has started nine games this season, with a 3-2 record and a 3.77 ERA. His WHIP stands at 1.21, and he has struck out 27 batters. The Cardinals will look to Mikolas to keep the Diamondbacks’ lineup in check during this night game. Both teams will aim to secure a win as they continue their season.

Cardinals Prepare for Upcoming Game

The St. Louis Cardinals have strong hitters this season. Lars Nootbaar leads the team with 7 home runs. He also has 31 runs and 25 RBIs.

Brendan Donovan is another key player for the Cardinals. He has a batting average of .323. Donovan has contributed 27 runs and 22 RBIs.

Willson Contreras is also making an impact. He has 6 home runs and 28 RBIs. His batting average stands at .250.

Arizona Diamondbacks Gear Up for the Game

Corbin Carroll is a standout player for the Diamondbacks. He has played in 50 games and leads the league with 15 home runs. Carroll also tops the league with 40 runs and has 34 RBIs. Geraldo Perdomo brings strength to the Diamondbacks’ lineup. He has a batting average of .306 and has played in 49 games. Perdomo has 6 home runs and 37 RBIs, ranking second in the league for RBIs. Eugenio Suárez adds power with 14 home runs in 50 games. He leads the league with 38 RBIs and has scored 30 runs. Suárez’s slugging percentage is .506, contributing to the team’s overall success.

Final Betting Pick

The Cardinals are a solid pick for the money line at 110. They have a better home record, winning 16 out of 24 games. Their pitching staff shows more strength with an ERA of 3.73 and a WHIP of 1.22, both better than the Diamondbacks’ numbers. This gives them an edge in controlling the game.

For the over/under, choosing under 8.5 is a reasonable option. The Cardinals allow fewer home runs, with only 37 given up this season. While both starting pitchers have had their ups and downs, the Cardinals’ overall pitching stats suggest a lower-scoring game. This makes under 8.5 a sensible choice.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.