Athletics vs Houston Astros MLB Betting Prediction
PublishedMay 28, 2025,            Posted By: Maria Uebelhor
Last updated:June 6, 2025 ,

MLB Athletics vs Houston Astros Prediction 5/28

On Wednesday, May 28, 2025, the Athletics will take on the Houston Astros at Daikin Park. The game is set to start at 2:10 PM and will be played at night. Fans can expect an exciting game between these two teams.

Athletics vs. Astros Betting Prediction

  • Money Line Prediction: Athletics MoneyLine +128. The Athletics have a better road record and face an Astros pitcher with a high ERA and WHIP, which could give them an edge.
  • Over/Under Prediction: Over 8.5 (-103). Both teams have shown strong hitting, and with the Astros’ starting pitcher struggling, more runs could be scored.

Team Trends

  • The Athletics have a home record of 9-19 and a road record of 14-13 this season.
  • Houston Astros have a division record of 9-6, while the Athletics have a division record of 8-11.
  • In their recent game against the Astros, the Athletics lost 11-1, with JP Sears allowing 9 runs in 3 1/3 innings.
  • Hunter Brown of the Astros pitched 6 innings with 8 strikeouts in the same game against the Athletics.
  • Jose Altuve hit 2 home runs and had 3 RBIs in the Astros’ 11-1 win over the Athletics.

Athletics vs Astros Preview

The Athletics and Astros will meet at Daikin Park on Wednesday night. The Athletics will rely on Luis Severino, who has an ERA of 4.11 and a WHIP of 1.26. He aims to keep the Astros’ hitters in check.

The Astros will counter with Lance McCullers Jr., who has faced challenges this season. He has an ERA of 6.57 and a WHIP of 2.03. Both teams look to gain ground in the standings with a win in this game.

Houston Astros: Key Players and Stats

Isaac Paredes leads the Astros with impressive stats. He has a batting average of .270 and an on-base percentage of .371. Paredes is first in the league with 11 home runs and 31 RBIs. Jeremy Peña has a strong presence at shortstop. He boasts a batting average of .298 and an on-base percentage of .362. Peña is second in the league with 27 runs and 27 RBIs. Christian Walker adds depth to the lineup. He has a batting average of .213 and an on-base percentage of .275. Walker is tied for second in the league with 7 home runs.

Oakland Athletics: Key Players and Stats

The Athletics are led by Tyler Soderstrom at first base. He has played 55 games, with a batting average of .264 and an on-base percentage of .332. Soderstrom leads the league with 10 home runs and 29 runs, making him a key player for the team. Jacob Wilson is another standout player for the Athletics. He has a batting average of .348 and an on-base percentage of .390. Wilson is dealing with a forearm injury, so his availability for the next game is uncertain. Shea Langeliers is the catcher for the Athletics. He has a batting average of .237 and an on-base percentage of .305. Langeliers ranks second on the team with 9 home runs and 23 runs.

Final Betting Pick

The Athletics have a solid chance with their MoneyLine at +128. They have a better road record, standing at 14-13, compared to the Astros’ 10-15 road record. The Astros’ starting pitcher, Lance McCullers Jr., has a high ERA of 6.57 and a WHIP of 2.03, which may work in the Athletics’ favor.

For the Over/Under prediction, going over 8.5 runs seems likely. Both teams have shown strong hitting, with the Athletics and Astros both having a team batting average of .256. With McCullers Jr. struggling, more runs could be scored, making the over a reasonable pick.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.