Boston Red Sox vs Cleveland Guardians MLB Betting Prediction

MLB Boston Red Sox vs Cleveland Guardians Prediction 4/26/25

The Boston Red Sox are set to play against the Cleveland Guardians at Progressive Field on Saturday, April 26, 2025. The game will start at 6:10 PM and will be played under the lights. Fans can expect an exciting evening of baseball action.

Red Sox vs. Guardians Betting Prediction

  • Money Line Prediction: Red Sox MoneyLine: 100. The Red Sox have a solid lineup with top hitters like Alex Bregman and Trevor Story. Walker Buehler’s pitching could give them an edge.
  • Over/Under Prediction: Over 7.5 (-114). Both teams have shown they can score, and with Buehler’s ERA at 4.23, runs could add up quickly.

Team Trends

  • The Boston Red Sox have a regular season record of 14-13 and are 1 game back in the AL East.
  • The Cleveland Guardians have a regular season record of 14-10 and are 0 games back in the AL Central.
  • In a recent game, the Boston Red Sox lost to the Seattle Mariners 4-3, despite hitting 2 home runs.
  • The Cleveland Guardians recently won against the New York Yankees 3-2, with Steven Kwan getting 2 hits.
  • Walker Buehler pitched 7 innings with 9 strikeouts for the Boston Red Sox in a win against the Chicago White Sox.

Red Sox vs Guardians Preview

The Boston Red Sox will send Walker Buehler to the mound against the Cleveland Guardians at Progressive Field. Buehler has started five games this season, recording a 3-1 record. He has an ERA of 4.23 and has struck out 26 batters in 27 2/3 innings. His performance will be key for the Red Sox as they aim to secure a win on the road.

On the other side, Doug Nikhazy will start for the Guardians. Nikhazy has not played any games this season, so his performance is uncertain. Fans will watch closely to see how he handles the Red Sox lineup. The game under the lights at 6:10 PM promises to be an interesting matchup between these teams.

Cleveland Guardians: Key Players and Stats

Steven Kwan leads the Cleveland Guardians in batting average. He has played 24 games with a .337 average. Kwan also ranks first in the league for runs with 17. Kyle Manzardo stands out with his power-hitting ability. He has hit 7 home runs, ranking first in the league. Manzardo also leads the team with 18 RBIs. José Ramírez provides solid support with his consistent performance. He has 5 home runs and 13 RBIs. Ramírez ranks second on the team in both categories.

Boston Red Sox: Top Performers and Pitching Insights

Alex Bregman stands out for the Boston Red Sox. He has a .320 batting average and leads the team with 5 home runs. Bregman also tops the league with 21 RBIs and 17 runs. Wilyer Abreu adds depth to the Red Sox lineup. He has a .271 average and 4 home runs. Abreu is second on the team with 15 runs and 15 RBIs. Trevor Story is another key player for the Red Sox. He has 5 home runs and a .297 average. Story also contributes with 15 RBIs and 12 runs.

Final Betting Pick

The Red Sox MoneyLine at 100 is a good pick due to their strong lineup. Alex Bregman and Trevor Story are key players with solid stats this season. Walker Buehler’s pitching adds to their chances, with a record of 3-1 and a WHIP of 1.19.

Choosing the Over 7.5 is also a smart move. Both teams have shown they can score, with the Red Sox having 28 home runs. Buehler’s ERA of 4.23 suggests runs could come easily, especially with hitters like Steven Kwan and Kyle Manzardo on the Guardians.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.