Chicago Cubs vs San Diego Padres MLB Betting Prediction

MLB Chicago Cubs vs San Diego Padres Prediction 4/15

The Chicago Cubs will take on the San Diego Padres at PETCO Park on Tuesday, April 15, 2025. The game is set to start at 9:40 PM and will be played under the night sky. Fans can expect an exciting game as these two teams meet in San Diego.

Cubs vs. Padres Betting Prediction

  • Money Line Prediction: Padres MoneyLine: 119. The Padres have a strong home record of 11-0 and a better overall season record of 14-3. Their pitching and hitting stats are also impressive, making them a good value as underdogs.
  • Over/Under Prediction: Under 7.5 (-106). Both teams have solid pitching, with the Padres having a 2.70 ERA and the Cubs’ pitcher, Shota Imanaga, showing a 2.70 ERA as well. This suggests a lower-scoring game.

Team Trends

  • The Chicago Cubs have a balanced road record of 7-4 this season.
  • The San Diego Padres are undefeated at home with an 11-0 record.
  • In a recent game against the Padres, the Cubs had 11 hits, but they lost 10-4.
  • Fernando Tatis Jr. hit two home runs in the Padres’ win over the Cubs.
  • Michael King pitched a complete game shutout for the Padres against the Rockies.

Cubs vs Padres Preview

The Chicago Cubs head to PETCO Park to face the San Diego Padres on Tuesday night. The game will begin at 9:40 PM. Shota Imanaga will start for the Cubs. He has a 2-1 record with a 2.70 ERA this season. In his last game against the Padres, he allowed only one run over 7 1/3 innings.

Randy Vásquez will pitch for the Padres. He has a 1-1 record and a 1.72 ERA. In his recent game against the Cubs, he pitched 4 2/3 innings and allowed two earned runs. Fans can look forward to seeing these pitchers compete again under the lights in San Diego.

San Diego Padres: Hitting and Pitching Power

Fernando Tatis Jr. is a standout player for the Padres. He has played 16 games with a batting average of .361. He leads the league in home runs with 6 and has scored 16 runs. Manny Machado is another key player for the Padres. He has played 17 games with a batting average of .317. Machado has scored 15 runs and has 6 RBIs. Xander Bogaerts adds depth to the lineup. He has played 17 games with a batting average of .288. Bogaerts has scored 8 runs and has 5 RBIs.

Chicago Cubs: Key Players and Pitching Insights

Kyle Tucker is a top hitter for the Cubs. He has played 19 games with a batting average of .307. Tucker leads the league with 5 home runs and 18 RBIs. Seiya Suzuki has been strong for the Cubs too. He has a batting average of .292 in 17 games. Suzuki is dealing with a wrist injury and may not play. Pete Crow-Armstrong adds to the Cubs’ lineup. He has played 19 games with a batting average of .257. Crow-Armstrong has scored 14 runs and hit 2 home runs.

Final Betting Pick

The Padres are a strong pick for the MoneyLine at 119. Their home record is perfect at 11-0, and they have a better overall season record than the Cubs. With a team ERA of 2.70, their pitching is solid, and their hitting stats show a .284 batting average, which ranks them second in the league.

Choosing the Under 7.5 is also a good option. Both teams have strong pitching, with Shota Imanaga and Randy Vásquez having identical ERAs of 2.70. The Padres’ pitching staff holds opponents to a .189 batting average, indicating a likely low-scoring game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.