Chicago Cubs vs St. Louis Cardinals MLB Betting Prediction
PublishedJune 23, 2025,            Posted By: Maria Uebelhor
Last updated:June 24, 2025 ,

MLB Chicago Cubs vs St. Louis Cardinals Prediction 6/23

On Monday, June 23, 2025, the Chicago Cubs will take on the St. Louis Cardinals at Busch Stadium in St. Louis, MO. The game starts at 7:45 PM under clear skies with a light breeze. Fans can catch the night game action on MARQ.

Cubs vs. Cardinals Betting Prediction

  • Money Line Prediction: Chicago Cubs MoneyLine: -110. The Cubs have a solid road record of 21-16 this season. Their offense shows power with 113 home runs, ranking 3rd in the league.
  • Over/Under Prediction: Over 9.0. Both starting pitchers have high ERAs, with Ben Brown at 5.57 and Matthew Liberatore at 4.08. This suggests potential for a high-scoring game.

Team Trends

  • The Chicago Cubs have a road record of 21-16 this season.
  • The St. Louis Cardinals hold a home record of 24-15 this season.
  • In their last game, the Chicago Cubs lost to the Seattle Mariners 14-6.
  • The St. Louis Cardinals lost their most recent game to the Cincinnati Reds 4-1.
  • The game will be played at Busch Stadium, with a clear sky and a light breeze expected.

Cubs vs Cardinals Preview

The Chicago Cubs visit the St. Louis Cardinals at Busch Stadium on Monday, June 23, 2025. The game starts at 7:45 PM, and fans can watch it on MARQ. The weather forecast shows clear skies and a light breeze, making it a pleasant night for baseball.

Ben Brown will pitch for the Cubs. His ERA is 5.57, and his WHIP is 1.48. Matthew Liberatore will start for the Cardinals. He has a 4.08 ERA and a WHIP of 1.16. Both pitchers have similar win-loss records, with Brown at 4-5 and Liberatore at 4-6. This game is set to be an exciting matchup between two division rivals.

St. Louis Cardinals: Home Team Highlights

The St. Louis Cardinals have several key players contributing to their lineup. Willson Contreras leads the team with 10 home runs and 50 RBIs. Brendan Donovan stands out with a .308 batting average, the highest among the top hitters. Nolan Arenado is another important player for the Cardinals. He has hit 10 home runs and driven in 39 runs. Masyn Winn adds to the lineup with a .255 batting average and 46 runs scored. On the pitching side, Matthew Liberatore is set to start. His ERA is 4.08 with a WHIP of 1.16. The Cardinals’ team ERA is 3.95, ranking them 18th this season.

Chicago Cubs: Away Team Insights

Seiya Suzuki is a key player for the Cubs. He has played 73 games with a batting average of .256. Suzuki leads the team with 20 home runs and 64 RBIs. Dansby Swanson is another important hitter. He has a .241 batting average and has played 76 games. Swanson has hit 14 home runs and scored 43 runs. The Cubs’ pitching staff has Ben Brown starting. Brown has a 5.57 ERA and a WHIP of 1.48. The Cubs’ team ERA is 3.84, ranking them 13th this season.

Final Betting Pick

The Cubs are a good pick for the MoneyLine at -110. They have a strong road record of 21-16, showing they can win away from home. Their offense is powerful, with 113 home runs, which ranks them 3rd in the league. This power can be a key factor against the Cardinals’ pitching.

The Over 9.0 is also a solid choice. Both starting pitchers, Ben Brown and Matthew Liberatore, have high ERAs of 5.57 and 4.08, respectively. This suggests that both teams might score a lot of runs. The Cubs’ recent games have shown they can score, making the Over a likely outcome.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.