The Chicago White Sox take on the Cleveland Guardians on Saturday, September 13, 2025, at 6:10 PM. The game will be held at Progressive Field in Cleveland, OH. Fans can expect a warm evening with overcast clouds and calm winds. Tune in to CHSN to catch all the action. The White Sox hold a record of 57-91, while the Guardians stand at 76-71 this season.

White Sox vs. Guardians Betting Prediction

• Money Line Prediction: Cleveland Guardians -167. The Guardians have a strong home record and are on a winning streak. Their recent form and home advantage make them a solid choice.
• Over/Under Prediction: Under 8.0 (-119). With Parker Messick’s low ERA and the White Sox’s recent struggles at the plate, a low-scoring game is likely.

Team Trends

• The Cleveland Guardians have a strong home record with 39 wins and 34 losses this season.
• The Chicago White Sox have struggled on the road, winning only 25 of their 73 away games.
• The Guardians are on a two-game winning streak and have won 8 of their last 10 games.
• The White Sox have a division record of 18 wins and 32 losses in the AL Central this season.
• The game will be played at Progressive Field with overcast clouds and calm winds.

White Sox vs Guardians Preview

The Chicago White Sox are set to play the Cleveland Guardians at Progressive Field. The White Sox have had a tough season, sitting at the bottom of their division. They have a record of 57-91. Despite this, they have won 7 of their last 10 games. Davis Martin will pitch for the White Sox. He has a 4.03 ERA and a 6-9 record.

The Cleveland Guardians are in a better position with a 76-71 record. They are second in the division and have won their last two games. Parker Messick will start for the Guardians. He has been effective with a 1.93 ERA and a 2-0 record. Fans can watch the game on CHSN. The weather is expected to be warm with overcast clouds.

Guardians Gear Up for Home Game

The Cleveland Guardians are ready to play at home. José Ramírez leads the team with a .283 batting average. He also has 28 home runs and 91 runs, both top in the team ranks. Kyle Manzardo is another strong player for the Guardians. He has played 127 games with a .239 batting average. Manzardo has hit 26 home runs, which is second on the team. Parker Messick is set to start as pitcher for the Guardians. He has an ERA of 1.93 and a WHIP of 1.33. Messick has a record of 2 wins and no losses this season.

White Sox Prepare for Away Challenge

The Chicago White Sox are set for their next game. Lenyn Sosa stands out with a .263 batting average. He has hit 20 home runs, leading the team in that category. Sosa also has 67 RBIs, which is the highest on the team. Miguel Vargas is another key player for the White Sox. He has played 125 games with a .231 batting average. Vargas has hit 14 home runs and scored 71 runs, ranking first on the team in runs. Davis Martin will be the starting pitcher for the White Sox. His ERA is 4.03, and his WHIP is 1.28. Martin has a record of 6 wins and 9 losses this season.

Final Betting Pick

The Cleveland Guardians are a strong pick for the money line at -167. They have a good home record of 39-34 and are on a winning streak. Parker Messick, with a low ERA of 1.93, is starting, which adds to their advantage.

The under 8.0 prediction looks solid given the White Sox’s recent struggles at the plate. They have a road record of 25-48 and were shut out in their last game against the Guardians. With Messick’s pitching and the White Sox’s hitting issues, a low-scoring game is likely.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.