Cleveland Guardians vs Cincinnati Reds MLB Betting Prediction

MLB Cleveland Guardians vs Cincinnati Reds Prediction 5/17

On Saturday, May 17, 2025, the Cleveland Guardians will play against the Cincinnati Reds at Great American Ball Park. The game is set to begin at 6:40 PM. Fans can look forward to an exciting evening as these two teams compete under the night sky.

Guardians vs. Reds Betting Prediction

  • Money Line Prediction: Reds MoneyLine: 108. The Reds have a solid home record and their recent form shows strong hitting performances. Their pitching stats are also better this season.
  • Over/Under Prediction: Over 9.5 (-116). Both teams have shown the ability to score runs, and the Reds’ recent games have seen high scores.

Team Trends

  • The Cleveland Guardians have a strong division record of 10-3 this season.
  • The Cincinnati Reds have a balanced home and road record, both at 11-12.
  • In a recent game against the Cincinnati Reds, Tanner Bibee of the Cleveland Guardians pitched 6 innings and allowed 10 hits.
  • José Ramírez hit a home run in the Cleveland Guardians’ recent game against the Cincinnati Reds.
  • Nick Martinez of the Cincinnati Reds pitched 7 innings with no runs allowed in a recent game against the Chicago White Sox.

Guardians vs Reds Preview

The Cleveland Guardians head to Great American Ball Park to take on the Cincinnati Reds on Saturday night. Slade Cecconi will start for the Guardians. He has yet to play this season, so fans will see how he performs in his first game.

Brent Suter will take the mound for the Reds. He has a 2.08 ERA over 21 2/3 innings this season. Suter has appeared in 14 games, but this will be only his second start. The Reds will look to him for a strong performance against the Guardians.

Reds Ready for Action at Home

Elly De La Cruz is leading the Reds with strong stats. He has 8 home runs, 30 runs, and 31 RBIs. These numbers rank him first in the league for each category. TJ Friedl is also contributing well. He has a batting average of .269 and is second on the team with 23 runs. Friedl is dealing with a wrist injury but is likely to play. Matt McLain has hit 6 home runs this season. He has 23 runs and 16 RBIs. McLain’s batting average is .184, which he will aim to improve.

Guardians Look to Make Impact on the Road

José Ramírez is a key player for the Guardians. He has played in 42 games with a .294 batting average. Ramírez has hit 9 home runs, placing him second in the league. Steven Kwan is another important player for the Guardians. He has a batting average of .320 over 44 games. Kwan leads the team with 26 runs and has 17 RBIs. Kyle Manzardo has made a mark with his power hitting. He leads the team with 10 home runs and 25 RBIs. However, his batting average is .222, which he might want to improve.

Final Betting Pick

The Reds MoneyLine pick at 108 looks solid. The Reds have a balanced record at home and on the road, and their recent games show strong hitting. Their batting average and on-base percentage rank better than the Guardians, which supports their ability to score runs. With the Reds’ pitching stats also ranking higher, they have a good chance to win.

The Over 9.5 prediction is based on both teams’ ability to score. The Reds have a higher slugging percentage and have shown they can hit home runs. Recent games for both teams have seen high scores, suggesting this game might follow the same pattern. The Guardians’ pitching has allowed a fair number of runs, which could lead to a high-scoring game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.