Cleveland Guardians vs Detroit Tigers MLB Betting Prediction

MLB Cleveland Guardians vs Detroit Tigers Prediction 5/22

On Thursday, May 22, 2025, the Cleveland Guardians will take on the Detroit Tigers at Comerica Park. The game is set to start at 6:40 PM under the night sky. Fans can expect an exciting evening as these teams meet on the field.

Guardians vs. Tigers Betting Prediction

  • Money Line Prediction: Tigers MoneyLine: -138. The Tigers have a better overall record and strong home performance. Their pitching and hitting stats are also better this season.
  • Over/Under Prediction: Under 8.0 (-112). Both teams have solid pitching, and the Tigers have a low ERA. This could lead to fewer runs scored.

Team Trends

  • The Cleveland Guardians have a strong home record of 14-8 this season.
  • Detroit Tigers have a better overall record this season at 33-17 compared to the Guardians’ 26-22.
  • Cleveland Guardians’ division record is 11-4, showing success within the AL Central.
  • In a recent game against the Minnesota Twins, Gavin Williams pitched 6 innings with only 2 hits allowed.
  • Detroit Tigers’ Riley Greene had a standout performance on May 20th, 2025, with 4 RBIs against the St. Louis Cardinals.

Guardians vs Tigers Preview

The Cleveland Guardians will visit the Detroit Tigers at Comerica Park on Thursday, May 22, 2025. The game will begin at 6:40 PM. Both teams are eager to improve their standings in the division.

Tanner Bibee will start on the mound for the Guardians. He has a record of 3-4 this season with an ERA of 4.06. Jack Flaherty will pitch for the Tigers. He holds a 2-5 record and an ERA of 4.44. Both pitchers aim to lead their teams to victory.

Detroit Tigers: A Balanced Attack

The Detroit Tigers have some standout hitters this season. Spencer Torkelson leads the team with a batting average of .249 and has hit 12 home runs. Riley Greene is not far behind, also with 12 home runs and a batting average of .287.

Kerry Carpenter adds depth to the lineup with a .278 batting average. He has contributed 10 home runs so far. These players are key to the Tigers’ offensive strength.

On the pitching side, Jack Flaherty has started nine games this season. He has an ERA of 4.44 and has struck out 56 batters. The Tigers’ pitching staff holds a team ERA of 3.32, ranking fifth in the league.

Cleveland Guardians: Key Players and Pitching

José Ramírez is a top player for the Cleveland Guardians. He has a batting average of .304 with 9 home runs. Ramírez also has 26 runs and 24 RBIs, making him a key player in the lineup. Steven Kwan adds to the Guardians’ offense with a batting average of .317. He has 4 home runs and leads the team with 27 runs. Kwan’s ability to get on base is important for the team’s success. Tanner Bibee is the starting pitcher for the Guardians. He has a record of 3-4 and an ERA of 4.06. Bibee has struck out 35 batters in 51 innings this season.

Final Betting Pick

The Tigers are favored on the money line at -138, and this pick is supported by their strong home record of 17-5. Their overall record of 33-17 is better than the Guardians’ 26-22. The Tigers also have a solid batting lineup, with Spencer Torkelson and Riley Greene leading in home runs and RBIs.

For the over/under bet, the under 8.0 at -112 seems reasonable. The Tigers have a team ERA of 3.32, which ranks fifth in the league. Both teams have shown strong pitching performances, suggesting a lower-scoring game. Jack Flaherty’s ERA of 4.44 and Tanner Bibee’s ERA of 4.06 indicate that runs might be limited in this game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.