The Cleveland Guardians will take on the Minnesota Twins at Target Field on Tuesday, May 20, 2025. The game is set to start at 7:40 PM and will be played at night. Fans can expect an exciting evening of baseball in Minnesota.

Guardians vs. Twins Betting Prediction

• Money Line Prediction: Guardians MoneyLine: -103. The Guardians have a strong division record and key hitters like José Ramírez and Steven Kwan. With Byron Buxton out for the Twins, the Guardians have a better chance.
• Over/Under Prediction: Under 7.5 (-112). Both teams have solid pitching performances, and the Twins have a top-ranked ERA. This suggests a low-scoring game.

Team Trends

• The Cleveland Guardians have a strong division record of 10-3 this season.
• The Minnesota Twins have a better home record at 15-6 compared to their road record of 11-15.
• In their recent game against the Cincinnati Reds, Cleveland Guardians pitcher Luis L. Ortiz had 7 strikeouts.
• Minnesota Twins pitcher Joe Ryan struck out 9 batters in a recent game against the Milwaukee Brewers.
• The Cleveland Guardians have hit 2 home runs in their game against the Milwaukee Brewers on May 14th, 2025.

Guardians vs Twins Preview

The Cleveland Guardians and Minnesota Twins are ready to meet at Target Field. The Guardians will have Gavin Williams on the mound. Williams has made nine starts this season, with a record of 3-2. His ERA stands at 4.29, and he has recorded 51 strikeouts. This game is a chance for him to improve his numbers.

On the other side, the Twins will start Chris Paddack. Paddack has also started nine games this season, holding a 2-3 record. His ERA is slightly better at 4.05, with 33 strikeouts. Both pitchers aim to give their teams a strong performance under the lights in Minnesota.

Twins’ Key Players and Pitching Strength

Byron Buxton leads the Minnesota Twins in several categories. He has 10 home runs and 33 runs, both ranked first in the league. However, Buxton is out with a concussion and is on the 7-day injured list. Trevor Larnach is another important player for the Twins. He has 7 home runs and 27 runs, both ranked second on the team. Larnach’s batting average is .244, and his on-base percentage is .325. Chris Paddack will start for the Twins. He has a 2-3 record with a 4.05 ERA this season. Paddack has 33 strikeouts in 46 2/3 innings pitched.

Guardians’ Key Players and Pitching Overview

José Ramírez is a standout player for the Cleveland Guardians. He has a batting average of .296 and an on-base percentage of .359. Ramírez also has 9 home runs and 23 RBIs, ranking second on the team. Steven Kwan is another important player for the Guardians. He leads the team with a .311 batting average and has an on-base percentage of .374. Kwan has scored 26 runs, the most on the team. Kyle Manzardo adds power to the lineup with 10 home runs. His slugging percentage is .493, and he has driven in 25 runs. Manzardo’s batting average is .221, but his impact is felt with his home runs and RBIs.

Final Betting Pick

The Guardians have a strong division record, which gives them an edge. José Ramírez and Steven Kwan are key hitters who can make a difference. With Byron Buxton out for the Twins, the Guardians have a better chance to win.

The under 7.5 prediction looks good due to the solid pitching from both teams. The Twins have a top-ranked ERA, suggesting a low-scoring game. Gavin Williams and Chris Paddack have similar stats, which may keep the score low.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.