Cleveland Guardians vs St. Louis Cardinals MLB Betting Prediction

MLB Guardians vs St. Louis Cardinals Prediction 9/22/2024

The Cleveland Guardians (90-66) travel to face off against the St. Louis Cardinals (78-77) on Sunday, September 22nd. This game will be played at Busch Stadium in St. Louis and televised on BSGL. The Cardinals are coming off a win in their previous game, while the Guardians are looking to get back on track from a loss to the Cardinals. First pitch is set for 1:15 CT.

Guardians vs. Cardinals Betting Prediction

  • Money Line Prediction: Cardinals (-111)
  • Over/Under Prediction: Over 7.5 Runs
  • The Cardinals have won 6 out of their last 9 home games.
  • In the last 15 games, the Cardinals have scored 4 or more runs in 9 games.
  • The Cardinals have a higher home win percentage (53.8%) compared to the Guardians’ away win percentage (52.5%).
  • The Cardinals have won 4 out of their last 6 games against teams with a winning record.
  • The Cardinals have a 5-5 record in their last 10 games, while the Guardians have a 6-4 record, indicating a competitive matchup with a slight edge to the home team.

Guardians vs Cardinals

cleveland guardians nba

It was a low-scoring game in the most recent game of this Cardinals vs. Guardians series. St. Louis went into the matchup as +111 underdogs and squeaked out a 6-5 win. The Cardinals had a big 4th inning, scoring four of their six runs. As for the Guardians, they scored their final run in the 5th.

Cleveland actually outhit the Cardinals in the game 10 to 8. Jose Ramirez was the game’s top hitter, going 2/4 with a home run. Miles Mikolas only went six innings for the Cardinals but gave up just one run and got the win.

St. Louis got a huge performance from Ivan Herrera, who went 2/3 with a home run and three RBIs. Jordan Walker also homered for the Cardinals’ offense.

With a 90-66 record, the Guardians are in 1st place in the AL Central with a 7.5-game lead over the Royals. Cleveland is 6-4 in their last 10 games and has a 28-15-6 series record this season.

The Guardians have an over/under record of 18-21 in games with a total of 7.5 runs, and their games have averaged 8.3 runs per game this season. On the run line, Cleveland is 42-38 on the road and 37-39 at home.

Gavin Williams Gets The Start For The Guardians

Gavin Williams gets the start for the Guardians today as he faces the Cardinals on the road. He has made 15 starts this season and has a record of 3-10 with an ERA of 5.12. Williams’ WHIP for the season is currently 1.39. In his 15 starts, he has turned in three quality starts and is averaging 9.73 strikeouts per nine innings. Williams has struggled on the road, coming in with a record of 3-3 and an ERA of 11.2 compared to 0-7 with a 6.98 ERA at home. Most recently, he gave up two earned runs in five innings of work, taking the loss vs. the Twins.

Guardians Offense Breakdown

For the season, the Guardians are averaging 4.4 runs per game, which is 15th in the league. At home, they have been a little better, putting up 4.7 runs per contest. As a team, they are batting .239, which is 14th in the league, and have the 11th most home runs in the league. José Ramirez and Josh Naylor are the team’s top power threats, with Ramirez’s 37 homers leading the team and Naylor’s 31 long balls coming in as the 2nd most on the team.

Looking at recent games, Andrés Giménez is batting .400 over his last five games, including one home run and three RBIs. He is also on a four-game hitting streak. José Ramirez has also been swinging the bat well of late, going 7/20 in his last five games with two homers and five RBIs.

As underdogs, the Cardinals have a 41-40 record and have won two straight games in that role. The team’s overall series record for the season is 25-20-5, and they have a 5-5 record in their last 10 games. Against the run line, St. Louis is 78-77, including a 40-40 record at home and 38-37 on the road.

St. Louis has a 43-37 home record this season and is 26-26 against NL Central teams. The Cardinals are currently 3rd in the NL Central, 10 games behind the Brewers, with a 78-77 overall record.

Andre Pallante Gets The Start For The Cardinals

St. Louis is sending right-hander Andre Pallante to the mound today vs. the Guardians. Pallante has made 18 starts this year and has a record of 7-8. His ERA for the season is 3.87, along with a WHIP of 1.35. In his 18 starts, Pallante has turned in six quality starts. Looking back at his most recent outing, Pallante was excellent, going seven innings vs. the Pirates and not giving up a run. He ended up with the win in that outing. Before that, he had lost three straight starts. Pallante’s ERA at home is 3.31, compared to 4.17 on the road.

Cardinals Offense Breakdown

st. louis cardinals

Heading into today’s game, the Cardinals are averaging 4.1 runs per game, which is 25th in the league. They have been a little better at home, averaging 4.2 runs per game. As a team, they are batting .246 and have the 10th fewest strikeouts in the league. St. Louis’ team OPS of .698 is 19th in the majors.

St. Louis has two players with over 20 homers, with Alec Burleson and Paul Goldschmidt both having gone deep 21 times this season. Brendan Donovan is batting .273 and is 2nd on the team in RBIs (68). Over his last seven games, Jordan Walker has gone 6/24 with two homers and seven RBIs.

Guardians vs Cardinals Prediction

Getting the Cardinals at -111 on the money line is a great value, and we see them coming away with a 6-5 win over the Guardians. With the payout being nearly the same as the payout for the over, we like the Cardinals to pick up the win.

Looking at the starting pitchers, Andre Pallante is projected to finish with four strikeouts compared to Gavin Williams, who is projected to strike out six. However, Pallante is projected to finish with a better ERA, as Williams is projected to give up five earned runs.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.