Houston Astros vs Cleveland Guardians MLB Betting Prediction
PublishedJune 6, 2025,            Posted By: Maria Uebelhor
Last updated:June 6, 2025 ,

MLB Houston Astros vs Cleveland Guardians Prediction 6/6

The Houston Astros will play against the Cleveland Guardians on Friday, June 6, 2025. The game will take place at Progressive Field in Cleveland, OH, starting at 7:10 PM. Fans can catch the action on CLEG, with weather expected to be mild and a light rain in the forecast.

Astros vs. Guardians Betting Prediction

  • Money Line Prediction: Astros MoneyLine at -107. The Astros have a slightly better overall record and recently won against the Pirates. The Guardians have a good home record, but the Astros’ recent form gives them the edge.
  • Over/Under Prediction: Under 8.5. The Guardians’ last game ended with a total of 4 runs, and the Astros have shown strong pitching recently, suggesting a low-scoring game.

Team Trends

  • The Houston Astros have a road record of 12-16 this season.
  • The Cleveland Guardians hold a home record of 17-11 this season.
  • In their last game, the Houston Astros won against the Pittsburgh Pirates with a score of 8-2.
  • The Cleveland Guardians lost their most recent game against the New York Yankees, with a score of 4-0.
  • The game will be played at Progressive Field, which is an outdoor stadium in Cleveland, OH.

Astros vs Guardians Preview

The Houston Astros will take the field against the Cleveland Guardians on Friday night. The game is set at Progressive Field, where the Astros will look to improve their season record. Colton Gordon will start on the mound for the Astros. Gordon has an ERA of 5.95 and is searching for his first win of the season.

For the Guardians, Logan Allen will be the starting pitcher. Allen has a 4.22 ERA and a 3-3 record this season. The Guardians hope to use their home-field advantage to secure a win. Fans can expect a mild evening with a light breeze and some rain in the forecast.

Cleveland Guardians: Home Team Overview

The Cleveland Guardians have a solid lineup with José Ramírez leading the team. Ramírez has played 59 games with a batting average of .330. He leads the team in home runs with 11 and runs scored with 38. Carlos Santana also contributes to the Guardians’ offense. He has a batting average of .261 over 57 games. Santana has hit 7 home runs and scored 31 runs, ranking second on the team in both categories. Logan Allen will be the starting pitcher for the Guardians. Allen has an ERA of 4.22 and a WHIP of 1.59. He holds a 3-3 win-loss record for the season.

Houston Astros: Road Team Analysis

Jeremy Peña is a key player for the Houston Astros. He has played in 62 games and has a batting average of .318. Peña leads the team with 34 runs. Isaac Paredes is another important hitter for the Astros. Paredes has hit 14 home runs in 61 games. He also has a .252 batting average, contributing to the team’s offense. Colton Gordon will be the starting pitcher for the Astros. Gordon has an ERA of 5.95 and a WHIP of 1.37. His win-loss record for the season is 0-1.

Final Betting Pick

The Astros’ MoneyLine at -107 is a solid pick due to their recent performance. They recently won 8-2 against the Pirates, showing strong hitting and pitching. Jeremy Peña and Isaac Paredes are key players, contributing home runs and RBIs in recent games.

Taking the Under 8.5 is a good choice given the Guardians’ recent low-scoring game against the Yankees, ending 4-0. The Astros’ pitching staff has been effective, with a team ERA of 3.56, ranked 9th. This suggests a tendency for low-scoring games, supporting the Under pick.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.