Houston Astros vs St. Louis Cardinals MLB Betting Prediction
PublishedApril 15, 2025,            Posted By: Maria Uebelhor
Last updated:April 15, 2025 ,

MLB Houston Astros vs St. Louis Cardinals Prediction 4/15

The Houston Astros will play the St. Louis Cardinals at Busch Stadium on Tuesday, April 15, 2025. The game will start at 7:45 PM during the night. Fans can expect an exciting game as these two teams meet on the field.

Astros vs. Cardinals Betting Prediction

  • Money Line Prediction: Cardinals MoneyLine: 110. The Cardinals have a better overall record and a strong home performance. Their batting average and on-base percentage are top in the league, which gives them an edge.
  • Over/Under Prediction: Under 7.5 (-116). Both starting pitchers have shown the ability to limit runs, and the Astros’ batting average is low. This suggests a lower-scoring game.

Team Trends

  • The Houston Astros have a current season record of 7-9, with a home record of 4-5 and a road record of 3-4.
  • The St. Louis Cardinals have a season record of 8-8, holding a strong home record of 7-3 but struggling on the road with a 1-5 record.
  • In a recent game on April 14th, 2025, the St. Louis Cardinals defeated the Houston Astros 8-3, with Sonny Gray pitching 7 innings allowing no runs.
  • On April 13th, 2025, the Houston Astros won against the Los Angeles Angels 7-3, with Hayden Wesneski striking out 10 batters in 6 innings.
  • The St. Louis Cardinals won against the Philadelphia Phillies 7-0 on April 13th, 2025, with Matthew Liberatore allowing only 3 hits in 6 innings.

Astros vs Cardinals Preview

The Houston Astros visit Busch Stadium to take on the St. Louis Cardinals. Hunter Brown will start for the Astros. In his last game against the Seattle Mariners, Brown pitched six innings without allowing a run. His season ERA is 2.00, showing strong performance in early games.

The Cardinals will counter with Erick Fedde on the mound. Fedde pitched six innings with no hits allowed against the Pittsburgh Pirates in his last outing. His current season ERA stands at 4.20. Both pitchers aim to lead their teams to a win in this night game.

Cardinals Look to Continue Strong Hitting

The St. Louis Cardinals have been hitting well this season. Brendan Donovan leads the team with a .391 batting average. He also has 11 RBIs, which is the best in the league. Lars Nootbaar has been getting on base often. His on-base percentage is .405. He has also scored 11 runs, leading the league in that category. Nolan Arenado is another key player for the Cardinals. He holds a .316 batting average and has 9 RBIs. Arenado is dealing with an illness and might not play.

Astros Aim to Overcome Cardinals

The Houston Astros have some key hitters this season. Isaac Paredes leads the team with a .262 batting average. He also has 3 home runs and 9 RBIs. Jose Altuve is another important player for the Astros. He has a .288 batting average with 3 home runs. Altuve also leads the team with 10 runs. Jeremy Peña adds to the lineup with his power. He has 3 home runs and 7 RBIs. His batting average is .207, but he still contributes with 9 runs. Hunter Brown is the starting pitcher for the Astros. In his recent games, Brown has pitched well. His ERA is 2.00 over 18 innings. Brown has not allowed a home run in his last two starts. His control has been strong, with no walks in his last two games. The Astros’ pitching staff ranks high in strikeouts. They have 174 strikeouts, which is the best in the league. The team also has a .205 batting average against them. This ranks them fourth in the league. Houston’s pitching will be important against the Cardinals’ strong hitters.

Final Betting Pick

The Cardinals have a strong case for the MoneyLine pick at 110. They have a solid home record of 7-3 and lead the league in batting average and on-base percentage. This gives them an advantage over the Astros, who have struggled with a 7-9 record and a lower batting average of .219.

For the Over/Under prediction, picking under 7.5 (-116) seems reasonable. Both starting pitchers, Hunter Brown and Erick Fedde, have shown they can limit runs. Brown has a 2.00 ERA, and Fedde allowed no runs in his last outing. The Astros’ low batting average further supports a lower-scoring game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.