Milwaukee Brewers vs San Diego Padres MLB Betting Prediction

MLB Milwaukee Brewers vs San Diego Padres Prediction 9/22

The Milwaukee Brewers will play against the San Diego Padres on Monday, September 22, 2025, at 9:40 PM. The game will take place at PETCO Park in San Diego, CA. Fans can catch the action on FDSWI, with the weather expected to be warm and scattered clouds in the sky.

Brewers vs. Padres Betting Prediction

  • Money Line Prediction: Milwaukee Brewers +106. The Brewers have a strong road record of 44-34 and a solid pitcher in Freddy Peralta with a 2.65 ERA.
  • Over/Under Prediction: Under 7.0 (-106). Both starting pitchers have low ERAs, with Peralta at 2.65 and Pivetta at 2.81, suggesting a low-scoring game.

Team Trends

  • The Milwaukee Brewers are leading the NL Central with a record of 95-61.
  • The San Diego Padres hold a second-place position in the NL West with a record of 85-71.
  • The Brewers have a road record of 44-34 this season.
  • The Padres have a strong home record of 47-28 this season.
  • The game will be played at PETCO Park, with weather conditions expected to be warm with scattered clouds.

Brewers vs Padres Preview

The Milwaukee Brewers are set to take on the San Diego Padres at PETCO Park. The Brewers hold a strong record of 95-61, leading their division. They are coming off a loss but have won six of their last ten games. Freddy Peralta will be on the mound for the Brewers. He has an ERA of 2.65 and a WHIP of 1.07, with a 17-6 record this season.

The Padres, with an 85-71 record, are second in their division. They have won their last two games and also have a 6-4 record in their last ten games. Nick Pivetta will start for the Padres. He has an ERA of 2.81 and a WHIP of 0.97, and his record is 13-5. This game will be an important one for both teams as they look to finish the season strong.

San Diego Padres: Key Players and Stats

Manny Machado stands out for the Padres this season. He has played 155 games with a batting average of .275. His 26 home runs and 93 RBIs lead the team. Luis Arraez is another important player for the Padres. He has a batting average of .287 over 149 games. Arraez has hit 7 home runs and scored 61 runs. Nick Pivetta will start as the pitcher for the Padres. His ERA is 2.81, and his WHIP is 0.97. Pivetta’s record this season is 13 wins and 5 losses.

Milwaukee Brewers: Key Players and Stats

Brice Turang is a standout player for the Brewers. He has played 150 games and holds a batting average of .286. Turang has hit 18 home runs and scored 95 runs, leading the team in both categories. William Contreras is another important player for the Brewers. He has a batting average of .265 over 147 games. Contreras has 17 home runs and 89 runs scored, making him second on the team in both areas. Freddy Peralta will be on the mound for the Brewers. His ERA is 2.65, and his WHIP is 1.07. Peralta’s record this season shows 17 wins and 6 losses.

Final Betting Pick

The Brewers’ money line at +106 is an appealing pick. They have a strong road record of 44-34, showing they perform well away from home. Freddy Peralta, their starting pitcher, has an impressive 2.65 ERA, which boosts their chances against the Padres.

The under 7.0 prediction looks solid due to both starting pitchers having low ERAs. Peralta’s ERA is 2.65, and Nick Pivetta of the Padres has a 2.81 ERA. This suggests a low-scoring game, making the under a sensible choice.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.