The Pittsburgh Pirates will play against the Arizona Diamondbacks at Chase Field. This game is set for Wednesday, May 28, 2025, at 3:40 PM. Fans can look forward to a night game under the lights.

Pirates vs. Diamondbacks Betting Prediction

• Money Line Prediction: Pirates MoneyLine +112. Paul Skenes has a strong ERA of 2.36, which gives the Pirates a good chance against the Diamondbacks’ Zac Gallen, who has a higher ERA of 5.25.
• Over/Under Prediction: Under 7.5 (-104). With Skenes’ solid pitching performance, runs may be limited, keeping the total score under 7.5.

Team Trends

• The Pittsburgh Pirates have a regular season record of 20-36 and are 14 games back in the NL Central.
• The Arizona Diamondbacks have a regular season record of 27-28 and are 7 games back in the NL West.
• In their recent game on May 26th, 2025, the Arizona Diamondbacks won 5-0 against the Pittsburgh Pirates.
• Pittsburgh Pirates’ home record stands at 13-16, while their road record is 7-20.
• Arizona Diamondbacks’ division record is 7-6, compared to the Pirates’ division record of 7-12.

Pirates vs Diamondbacks Preview

The Pittsburgh Pirates will travel to Arizona to play the Diamondbacks at Chase Field. This game will start in the evening, making it a night game. Fans can expect a pitching matchup with Paul Skenes starting for the Pirates and Zac Gallen for the Diamondbacks.

Paul Skenes has been solid for the Pirates with an ERA of 2.36 and a WHIP of 0.95. On the other side, Zac Gallen will take the mound for the Diamondbacks. Gallen has an ERA of 5.25 and a WHIP of 1.36. The Pirates will aim to take advantage of Gallen’s higher ERA in this game.

Arizona Diamondbacks: Key Players and Performance

The Arizona Diamondbacks have some standout hitters this season. Geraldo Perdomo is hitting .296 with 6 home runs. Eugenio Suárez leads the team with 15 home runs and 41 RBIs. Josh Naylor is contributing with a .291 batting average and 6 home runs. As a team, the Diamondbacks have a batting average of .256. They rank 3rd in on-base percentage and 4th in slugging percentage. The team has hit 76 home runs and leads the league with 109 doubles. On the pitching side, Zac Gallen will start for the Diamondbacks. He has an ERA of 5.25 and a WHIP of 1.36. The team has a 4.65 ERA, ranking 24th in the league, but they have 25 quality starts, which ranks 3rd.

Pittsburgh Pirates: Key Players and Season Insights

Andrew McCutchen leads the Pirates with a .261 batting average. He has 3 home runs and 15 runs scored. His on-base percentage stands at .371, making him a key player for the Pirates. Ke’Bryan Hayes has played in 52 games this season. He has a batting average of .226 with 1 home run. Hayes leads the team with 15 RBIs, contributing significantly to their offense. The Pirates’ starting pitcher, Paul Skenes, has an ERA of 2.36. His WHIP is 0.95, showing his effectiveness on the mound. The team’s overall ERA is 4.05, placing them 20th in the league.

Final Betting Pick

The Pirates’ MoneyLine at +112 is a solid pick because of Paul Skenes’ impressive ERA of 2.36. His strong pitching can limit the Diamondbacks’ hitters, even though they have a good batting average. Skenes’ ability to keep runs low gives the Pirates a chance to win.

Choosing the Under 7.5 is also a good option. Skenes’ pitching can keep the score low, and Zac Gallen’s higher ERA of 5.25 might not lead to many runs either. Both teams have shown they can have low-scoring games, which supports this prediction.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.