The San Diego Padres will visit the Chicago Cubs at Wrigley Field on Friday, April 04, 2025. The game is set to start at 2:20 PM. As the regular season begins, fans will look back at spring training and last year’s stats to gauge how these teams might perform.

Padres vs. Cubs Betting Prediction

• Money Line Prediction: Padres MoneyLine: 146
  The Padres have a strong start to the season with a 7-0 record. Their pitching and hitting stats are impressive, making them a good value as the underdog.
• Over/Under Prediction: Under 6.5 (104)
  Both starting pitchers have low ERAs early in the season. The Padres’ strong pitching could keep the total runs low.

Team Trends

• The San Diego Padres have an unbeaten regular season record of 7-0, with all wins at home.
• The Chicago Cubs have a regular season record of 5-4, performing better on the road with a 5-2 record.
• During spring training, the Padres’ Dylan Cease had a strong performance against the Guardians, striking out 7 in over 6 innings.
• Seiya Suzuki of the Cubs excelled in spring training against the Athletics, hitting 2 home runs and driving in 5 runs.
• In a spring training game against the Braves, Padres pitcher Nick Pivetta allowed only 1 hit over 7 innings.

Padres vs Cubs Preview

The San Diego Padres will take on the Chicago Cubs at Wrigley Field on Friday. The game will start at 2:20 PM. The Padres will have Randy Vásquez on the mound. In his recent outing against the Braves, he pitched six innings without allowing a run. Vásquez had a solid spring training, with a 3.38 ERA in three appearances.

For the Cubs, Shota Imanaga will start. Imanaga has shown strong performances early in the season. He pitched seven innings and allowed just one run against the Diamondbacks. During spring training, Imanaga had a higher ERA of 5.73 but managed to record 13 strikeouts in 11 innings. Both pitchers will look to continue their form in this game.

Chicago Cubs Early Season Outlook

The Chicago Cubs have started the season with promising hitting stats. Kyle Tucker stands out with a .324 batting average and four home runs. Seiya Suzuki also contributes with a .275 average and four home runs. Pitching for the Cubs has been led by Shota Imanaga. In his two regular season games, Imanaga has a 1-0 record with an ERA of .82. He pitched seven innings against the Diamondbacks, allowing only one run. The Cubs’ team stats show strong offensive numbers. They have a .255 batting average and lead the league in doubles and walks. However, their pitching has room for improvement, with a team ERA of 5.13.

San Diego Padres: Early Season Momentum

The San Diego Padres are off to a strong start in the regular season. Fernando Tatis Jr. is leading the team with a .423 batting average. Jackson Merrill is also performing well, hitting .417 with two home runs and eight RBIs. Manny Machado, despite dealing with a calf issue, is batting .400. Randy Vásquez is the starting pitcher for the Padres in this game. In his first regular season game, he pitched six innings against the Braves without allowing a run. During spring training, he had a 3.38 ERA over eight innings. The Padres’ team stats are impressive this season. They have a .298 batting average and rank second in stolen bases. Their pitching staff has a 1.57 ERA, the best in the league so far.

Final Betting Pick

The Padres are a strong pick for the MoneyLine at +146. They have started the season with a perfect 7-0 record. Their pitching is solid, with a team ERA of 1.57, which ranks first. Randy Vásquez has not allowed a run in his first start, showing he can keep hitters in check. Their batting is also strong, with Fernando Tatis Jr. and Jackson Merrill both hitting over .400.

The Under 6.5 is a good choice because both starting pitchers have low ERAs. Vásquez has a 0.00 ERA, and Shota Imanaga of the Cubs has a 0.82 ERA. The Padres’ pitching staff has allowed the fewest runs in the league. With both teams showing strong pitching early in the season, this game could see fewer runs scored.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.