San Diego Padres vs Toronto Blue Jays MLB Betting Prediction
PublishedMay 22, 2025,            Posted By: Maria Uebelhor
Last updated:May 22, 2025 ,

MLB San Diego Padres vs Toronto Blue Jays Prediction 5/22

On Thursday, May 22, 2025, the San Diego Padres will play against the Toronto Blue Jays at Rogers Centre. The game is scheduled to start at 1:07 PM and will be played under the night sky. Fans can expect an exciting game as these two teams meet on the field.

Padres vs. Blue Jays Betting Prediction

  • Money Line Prediction: Blue Jays MoneyLine: 103. The Blue Jays have won their last two games against the Padres, and Bowden Francis is looking to improve his record. The Padres have struggled recently, losing five straight games.
  • Over/Under Prediction: Under 9.0 (-113). Both teams have shown strong pitching performances recently, and the Padres have not been scoring many runs in their last few games.

Team Trends

  • The San Diego Padres have a strong division record of 7-1 this season.
  • Toronto Blue Jays have an even overall record of 24-24 this season.
  • In their recent game on May 21st, 2025, the Blue Jays defeated the Padres 14-0.
  • Kevin Gausman of the Blue Jays pitched 7 innings with 9 strikeouts and no runs allowed on May 21st, 2025.
  • Fernando Tatis Jr. hit a home run for the Padres against the Mariners on May 18th, 2025.

Padres vs Blue Jays Preview

The Padres and Blue Jays will meet at Rogers Centre on Thursday, May 22, 2025, for a night game. The Padres will have Stephen Kolek on the mound. Kolek has started three games this season with a 2-1 record and a 2.33 ERA. He has pitched 19 1/3 innings and struck out 15 batters.

On the other side, the Blue Jays will start Bowden Francis. Francis has made nine starts this season, holding a 2-6 record with a 5.63 ERA. He has pitched 46 1/3 innings and struck out 36 batters. Fans will be watching to see how both pitchers perform in this game.

Toronto Blue Jays: Home Team Overview

The Toronto Blue Jays are having a solid season at the plate. Vladimir Guerrero Jr. leads the team in runs with 28, which ranks first in the league. Bo Bichette tops the team in RBIs with 24, also leading the league. Bowden Francis is set to start on the mound for the Blue Jays. He has a record of 2-6 with an ERA of 5.63 over nine starts. Francis has struck out 36 batters in 46 1/3 innings pitched. The Blue Jays have a team batting average of .250, which ranks 11th in the league. They have hit 44 home runs, placing them 15th. On the pitching side, the team has a 4.13 ERA, ranking 21st.

San Diego Padres: A Look at the Away Team

The San Diego Padres have been strong at the plate this season. Fernando Tatis Jr. is a standout player, leading the league in home runs with 12. He also ranks first in runs with 37 and RBIs with 27. Manny Machado adds to the lineup with a batting average of .314. Xander Bogaerts has contributed, too, with 20 RBIs and 20 runs. The team has a batting average of .257, placing them 7th in the league. They have hit 41 home runs, ranking them 17th. Stephen Kolek will start on the mound for the Padres. He has a record of 2-1 with an ERA of 2.33 over three starts. Kolek has struck out 15 batters in 19 1/3 innings pitched.

Final Betting Pick

The Blue Jays MoneyLine at 103 looks appealing. They have a recent winning streak against the Padres, who are struggling with five straight losses. Bowden Francis aims to improve his record, and the Blue Jays’ recent performances suggest they can continue their success.

For the Over/Under prediction, going Under 9.0 seems reasonable. Both teams have shown strong pitching, and the Padres’ recent low-scoring games support this. Stephen Kolek’s solid ERA and the Blue Jays’ ability to limit runs make the Under a solid choice.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.