San Francisco Giants vs Chicago Cubs MLB Betting Prediction
PublishedMay 5, 2025,            Posted By: Maria Uebelhor
Last updated:May 5, 2025 ,

MLB San Francisco Giants vs Chicago Cubs Prediction 5/5

The San Francisco Giants will visit the Chicago Cubs at Wrigley Field on Monday, May 05, 2025. The game is set to begin at 7:40 PM and will take place at night. Fans can look forward to seeing these teams compete under the lights.

Giants vs. Cubs Betting Prediction

  • Money Line Prediction: Giants MoneyLine: 124. The Giants have a slightly better record and a strong recent performance. Their pitching has been solid, and they have a good chance to win.
  • Over/Under Prediction: Over 7.5 (-109). Both teams have strong hitters, and the Cubs have a high slugging percentage. This could lead to a high-scoring game.

Team Trends

  • The San Francisco Giants have a current record of 22-13, placing them 1 game back in the NL West.
  • The Chicago Cubs have a road record of 12-7, which is better than their home record of 9-7.
  • In their recent game against the Colorado Rockies, Giants’ pitcher Logan Webb allowed only 1 earned run in 7 innings.
  • The Cubs secured a 10-0 win against the Milwaukee Brewers with 3 home runs on May 2, 2025.
  • Willy Adames hit 2 home runs for the Giants in their 9-3 win over the Rockies on May 4, 2025.

Giants vs Cubs Preview

The San Francisco Giants will take on the Chicago Cubs at Wrigley Field on Monday night. Landen Roupp will start for the Giants. He has a 2-2 record with an ERA of 5.10 over 30 innings this season. Roupp will look to improve his stats in this game.

Matthew Boyd will pitch for the Cubs. Boyd has also recorded a 2-2 record, but with a lower ERA of 2.70 over 33 1/3 innings. Fans will watch to see how Boyd performs against the Giants’ lineup. This game could be a test for both pitchers as they aim for a win.

Cubs Ready to Swing Big

The Chicago Cubs have been strong at the plate this season. Kyle Tucker leads the team with a .292 batting average and nine home runs. His 30 runs and 30 RBI are both first in the league.

Pete Crow-Armstrong also has nine home runs, matching Tucker’s power. He holds a .272 batting average and has driven in 26 runs. Seiya Suzuki shares the home run lead with nine, adding 29 RBI.

Matthew Boyd will start on the mound for the Cubs. Boyd has a 2-2 record with a 2.70 ERA this season. He has struck out 30 batters in 33 1/3 innings pitched.

Giants Look to Make Their Mark

The San Francisco Giants have some strong hitters this season. Jung Hoo Lee leads the team with a .305 batting average. He also has 25 runs and 20 RBI, both among the top in the league. Matt Chapman is another key player for the Giants. He has hit seven home runs and has 21 RBI. His batting average is lower at .198, but he has a good on-base percentage of .345. Landen Roupp will be on the mound for the Giants. He has a 2-2 record with a 5.10 ERA this season. In 30 innings, he has struck out 35 batters.

Final Betting Pick

The Giants are a solid pick for the money line at 124. They have a slightly better record than the Cubs and have been performing well recently. Their pitching has been strong, with a team ERA of 3.50, which ranks 7th in the league. This gives them a good chance to win against the Cubs, who have an ERA of 3.85.

The over 7.5 prediction is also a good choice. Both teams have strong hitters, with the Cubs leading the league in batting average and slugging percentage. The Giants have shown they can score runs, as seen in their recent games against the Rockies. With both teams having powerful offenses, a high-scoring game is likely.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.