St. Louis Cardinals vs Chicago Cubs MLB Betting Prediction

MLB St. Louis Cardinals vs Chicago Cubs Prediction 7/4

The St. Louis Cardinals will play against the Chicago Cubs on Friday, July 4, 2025. The game will take place at Wrigley Field in Chicago, IL, starting at 2:20 PM. Fans can catch the afternoon game on APLTV, with weather conditions expected to be warm and breezy under broken clouds.

Cardinals vs. Cubs Betting Prediction

  • Money Line Prediction: Cubs -155. The Cubs have a strong home record of 28-15. They are also on a winning streak at home, with three recent wins against the Guardians.
  • Over/Under Prediction: Under 10.0 (-118). The Cardinals have struggled offensively in recent games, scoring no runs in their last three outings. The Cubs also had a low-scoring game recently, winning 1-0.

Team Trends

  • The Chicago Cubs have a strong home record this season, standing at 28-15.
  • The St. Louis Cardinals have struggled on the road, with a record of 21-24.
  • In their last game, the Cubs secured a 1-0 win against the Cleveland Guardians at home.
  • The Cardinals have lost their last three games, all against the Pittsburgh Pirates.
  • The Cardinals’ manager is Oliver Marmol, while the Cubs are managed by Craig Counsell.

Cardinals vs Cubs Preview

The St. Louis Cardinals and Chicago Cubs are ready to meet at Wrigley Field for an afternoon game on July 4, 2025. This rivalry game features two teams from the NL Central, with the Cardinals looking to gain ground in the standings. Fans can expect a warm day with a light breeze, making it a perfect setting for baseball.

Miles Mikolas will take the mound for the Cardinals. He brings a 4.76 ERA and a 1.32 WHIP into the game. The Cubs will counter with Colin Rea, who has a 4.37 ERA and a 1.37 WHIP. Both pitchers have had their ups and downs this season, so it will be interesting to see who can control the game from the start.

Chicago Cubs: Key Players and Performance

Seiya Suzuki is leading the Chicago Cubs in home runs and RBI. He has hit 23 home runs and driven in 73 runs. Suzuki’s batting average is .261, and he has played 83 games so far.

Michael Busch is another important player for the Cubs. He has a batting average of .277 and has hit 14 home runs. Busch has also contributed with 50 RBI in 81 games.

Dansby Swanson and Nico Hoerner add depth to the Cubs’ lineup. Swanson has hit 14 home runs and scored 48 runs. Hoerner has a batting average of .285 and has scored 47 runs this season.

St. Louis Cardinals: Key Contributors and Game Insights

Willson Contreras stands out for the Cardinals. He has played 82 games with a batting average of .248. Contreras leads the team with 11 home runs and 51 RBI. Brendan Donovan is another key player for St. Louis. He has a .293 batting average and has scored 45 runs. Donovan also contributes with 31 RBI across 80 games. Nolan Arenado adds strength to the lineup. He has hit 10 home runs and has a .247 batting average. Arenado has also driven in 41 runs this season.

Final Betting Pick

The Cubs are a strong pick for the money line at -155. They have a solid home record of 28-15 and are on a winning streak at Wrigley Field. Their recent games against the Guardians show they can win close games, including a 1-0 victory.

The under 10.0 prediction at -118 is also a good choice. The Cardinals have not scored in their last three games, which indicates offensive struggles. The Cubs’ recent low-scoring 1-0 win suggests a focus on pitching and defense, making a high-scoring game unlikely.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.