St. Louis Cardinals vs Pittsburgh Pirates MLB Betting Prediction

MLB St. Louis Cardinals vs Pittsburgh Pirates Prediction 4/8

The St. Louis Cardinals will travel to PNC Park to take on the Pittsburgh Pirates on Tuesday, April 08, 2025. The game is set to begin at 6:40 PM and will be played under the lights. Fans can expect an exciting night of baseball action.

Cardinals vs. Pirates Betting Prediction

  • Money Line Prediction: Cardinals MoneyLine 116. The Cardinals have a strong hitting lineup and lead the league in batting average and on-base percentage. Despite being the underdog, their offensive strength offers good value.
  • Over/Under Prediction: Under 6.5 (100). Both teams have shown struggles in hitting, with the Pirates ranking low in batting average and slugging percentage. With strong pitching from Skenes, a low-scoring game is likely.

Team Trends

  • The St. Louis Cardinals have not won a game on the road this season, with a road record of 0-4.
  • Pittsburgh Pirates’ pitcher Carmen Mlodzinski allowed only 1 run in 5 innings against the Cardinals on April 7th, 2025.
  • St. Louis Cardinals’ Brendan Donovan had 3 hits in the game against the Boston Red Sox on April 6th, 2025.
  • Pirates’ pitcher Andrew Heaney struck out 10 batters in 7 innings against the Yankees on April 6th, 2025.
  • St. Louis Cardinals’ Iván Herrera hit 3 home runs and had 6 RBIs against the Angels on April 2nd, 2025.

Cardinals vs Pirates Preview

The St. Louis Cardinals are set to take on the Pittsburgh Pirates at PNC Park. Sonny Gray will start for the Cardinals. He has a 1-0 record this season with an ERA of 5.73. Gray pitched six innings against the Los Angeles Angels, striking out nine batters but allowing five runs. He will aim to improve his performance in this game.

The Pirates will have Paul Skenes on the mound. Skenes has been strong this season, boasting a 1.46 ERA. In his last outing against the Tampa Bay Rays, he allowed only one run over seven innings. The Pirates will look to Skenes to keep the Cardinals’ bats in check. Both teams will be eager to secure a win in this division game.

Pittsburgh Pirates: Key Players and Team Overview

The Pittsburgh Pirates have some standout hitters this season. Oneil Cruz leads the team with 2 home runs and 5 RBIs. Isiah Kiner-Falefa has a strong batting average of .343 and leads the team in runs with 6. Ke’Bryan Hayes also contributes with a .263 batting average. He shares the team lead with 5 RBIs alongside Cruz. These players are vital to the Pirates’ offensive efforts. Paul Skenes is the starting pitcher for the upcoming game. He has a solid ERA of 1.46 over two games this season. Skenes has pitched 12 1/3 innings with 13 strikeouts and no home runs allowed.

St. Louis Cardinals: Players to Watch and Game Strategy

The Cardinals have some strong hitters this season. Lars Nootbaar is playing well with a .302 batting average and 10 runs. Brendan Donovan also adds to the lineup with a .375 batting average and 9 RBIs. Iván Herrera has been impressive with 4 home runs and 11 RBIs, but he is out with a knee injury. Sonny Gray is the starting pitcher for the Cardinals. He has pitched 11 innings this season with a 5.73 ERA. Gray has allowed 5 runs in his recent game against the Angels. He will look to improve his performance in the upcoming game. The Cardinals lead the league with a .297 batting average and a .374 on-base percentage. They have hit 16 home runs this season, which ranks them 5th. However, their pitching has struggled with a team ERA of 6.18, ranking last in the league.

Final Betting Pick

The Cardinals MoneyLine at 116 is a good pick because of their strong hitting lineup. They lead the league in batting average and on-base percentage. Even with Iván Herrera out, players like Lars Nootbaar and Brendan Donovan are performing well. This gives the Cardinals a solid chance to win, despite being the underdog.

The Under 6.5 (100) is a smart choice due to both teams’ struggles with hitting. The Pirates rank low in batting average and slugging percentage. With Paul Skenes pitching effectively for the Pirates, a low-scoring game is likely. Skenes has allowed only one run in his last two starts, making it hard for the Cardinals to score many runs.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.