Louisville Cardinals vs Notre Dame Fighting Irish NCAAF Betting Prediction

NCAAF Louisville vs Notre Dame Prediction 9/28/2024

The Louisville Cardinals (3-0) face off against the Notre Dame Fighting Irish (3-1) on Saturday, September 28th. This game will be played at Notre Dame Stadium in Notre Dame and televised on PEAC. Both team’s come into this one having won their previous games. Kickoff is set for 3:30 ET.

Louisville Cardinals vs Notre Dame Fighting Irish

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Louisville Offense Breakdown

Quarterback Tyler Shough led Louisville’s offense to a 31-19 win over Georgia Tech, throwing for 269 yards and two touchdowns. Shough completed 68.4% of his passes and ended the game with a passer rating of 146.27. Ja’Corey Brooks was his top target, catching four passes for 125 yards and one touchdown.

The Cardinals’ offense totaled 332 yards, with just 63 yards coming on the ground. Donald Chaney led the team in rushing with 23 yards on 10 carries.

Notre Dame Offense Breakdown

Notre Dame’s offense was dominant in their 28-3 win, racking up 428 total yards and 24 first downs. The ground game was particularly strong, with the Irish rushing for 270 yards and three touchdowns. Quarterback Riley Leonard also contributed to the rushing attack, gaining 143 yards on 12 carries and scoring twice on the ground.

Leonard completed 16 of 25 passes for 154 yards and a touchdown, ending the game with a passer rating of 94.42. Beaux Collins led the receiving corps with four catches for 60 yards and one touchdown.

Louisville Team Defense

Louisville’s defense will need to tighten up after allowing 410 total yards to Georgia Tech in their last game. The Cardinals gave up 312 passing yards on 21 completions, and their secondary will need to improve. On the ground, they allowed 98 yards and two rushing touchdowns. Overall, Louisville’s defense will be looking for better results in their next game.

Louisville Team Defense

Notre Dame’s defense was effective in their most recent game, holding Miami (OH) to just 3 points and 229 total yards. The Fighting Irish secondary was particularly strong, picking off two passes and limiting Miami (OH) to 119 passing yards. Notre Dame’s run defense was also solid, allowing just 110 yards on the ground.

Louisville vs Notre Dame Trends

  • When looking at their past five road matchups, Louisville has an ATS record of 1-4 while averaging 21 per game. The team went 2-3 overall in these games.
  • Across their last three home contests, Notre Dame has been good against the spread posting a mark of 3-0. Their overall mark in these games was 3-0, while averaging 48 points per game.
  • The last ten games that Louisville was the underdog, they have an ATS mark of 4-6 while going 4-6 straight up.
  • As the betting favorite, the Notre Dame Fighting Irish have an ATS mark of just 6-4 in their last ten games. Notre Dame posted a straight up mark of 7-3 in these matchups.

Cardinals vs Fighting Irish Prediction

Our projection for the Louisville vs. Notre Dame matchup is a 31-22 win for the Cardinals, who are currently favored by -6.5 points. We like Louisville to not only win straight-up, but also to cover the spread as road underdogs.

With the over/under line set at 47.5 points, our projection of 53 combined points suggests that taking the over is the best play for this game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.