The SMU Mustangs will take on the TCU Horned Frogs in Week 4 of the 2025 regular season. The game is set for Saturday, September 20, 2025, at 12:00 PM. It will be held at Amon G. Carter Stadium in Fort Worth, TX, and will air on ESPN2.

SMU vs. TCU Betting Prediction

• Money Line Prediction: TCU Horned Frogs -244. TCU is unbeaten this season and has a strong home record. They won their last home game against Abilene Christian, 42-21.
• Over/Under Prediction: Under 64.5. TCU’s defense has been solid, allowing only 35 points this season. SMU’s last game also stayed under the total with a 28-10 win over Missouri State.

Team Trends

• SMU Mustangs hold a 1-0 record on the road this season.
• TCU Horned Frogs have a 1-0 home record this season.
• In their last game, SMU defeated Missouri State Bears 28-10.
• TCU won their last home game against Abilene Christian Wildcats with a score of 42-21.
• SMU ranks 5th in sacks with 9 this season.

SMU vs TCU Preview

The SMU Mustangs are heading to Fort Worth for a game against the TCU Horned Frogs. SMU holds a 2-1 record this season and comes off a win. They have been strong on the road with a 1-0 record away from home. The Mustangs aim to continue their positive momentum as they step into Amon G. Carter Stadium.

The TCU Horned Frogs enter this game with a perfect 2-0 record. They have secured wins both at home and on the road. TCU is on a 2-game win streak and will look to defend their home turf. This game is set to be an exciting contest with both teams eager to add another win to their records.

TCU Horned Frogs Overview

The TCU Horned Frogs are part of the Big 12 Conference. They play at Amon G. Carter Stadium. This season, they hold a 2-0 record, with a win both at home and on the road.

Josh Hoover is the top quarterback for TCU. In two games, he has thrown for 621 yards, ranking first on the team. He also has six passing touchdowns and just one interception.

Their team offense has scored 90 points this season, ranking 43rd. They have 645 passing yards and 388 rushing yards. On defense, TCU has allowed 35 points and recorded six sacks.

SMU Mustangs Ready for the Road

The SMU Mustangs play in the Atlantic Coast Conference. They hold a 2-1 record this season. Their last postseason game was against Penn State, where they lost 38-10.

Kevin Jennings leads the Mustangs as their top quarterback. He has played in three games, throwing for 836 yards. Jennings also has six passing touchdowns and three interceptions.

TJ Harden is the standout running back for SMU. He has rushed for 253 yards and scored five touchdowns in three games. On the defense, SMU has allowed 71 points and recorded nine sacks.

Final Betting Pick

TCU Horned Frogs have been strong at home this season, winning their last game against Abilene Christian by a score of 42-21. Their defense has been effective, allowing only 35 points this season. This makes the money line prediction of TCU at -244 a solid choice.

The prediction for the total points to be under 64.5 is also supported by recent performances. TCU’s defense has been tight, and SMU’s last game ended with a total of 38 points. Both teams have shown the ability to keep games low-scoring, making the under a reasonable bet.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.