Get ready for an exciting game as the Tulane Green Wave take on the Ole Miss Rebels on Saturday, September 20, 2025. The game kicks off at 3:30 PM ET at Vaught-Hemingway Stadium in Oxford, MS. Both teams come into this matchup with perfect 3-0 records, making this a must-watch game. You can catch all the action live on ESPN.

Tulane vs. Ole Miss Betting Prediction

• Money Line Prediction: Ole Miss at -434. Ole Miss is strong at home with a 2-0 record this season. They are ranked #13 in the AP poll, which suggests a good performance.
• Over/Under Prediction: Over 61.5. Both teams have been scoring well, with Ole Miss having a high offensive rank. The Over has hit in all of Ole Miss’s games this season.

Team Trends

• Tulane Green Wave has a perfect 3-0 record this season, with one win on the road.
• Ole Miss Rebels is ranked #13 in the AP Poll and #11 in the Coaches Poll.
• The game will be played at Vaught-Hemingway Stadium in Oxford, MS, which is the home field for Ole Miss Rebels.
• Ole Miss Rebels has a strong home record this season, winning both of their home games.
• Tulane Green Wave’s rushing offense ranks 19th this season with 670 yards.

Tulane vs Ole Miss Preview

The Tulane Green Wave are ready to take on the Ole Miss Rebels in Week 4 of the 2025 season. Both teams have started strong, each holding a 3-0 record. Tulane has shown their strength on the road with a 1-0 record away from home. They are currently on a 3-game win streak, making them a team to watch in the American Conference.

Ole Miss enters the game with a solid 2-0 home record. Ranked 13th in the AP Poll and 11th in the Coaches Poll, they are looking to maintain their momentum. The Rebels have also won their last three games, including two conference victories. This matchup at Vaught-Hemingway Stadium promises to be a key test for both teams. Catch the game live on ESPN at 3:30 PM ET.

Strong Start and High Rankings

Ole Miss Rebels hold a strong position in both the AP and Coaches Polls, ranked #13 and #11 respectively. They are part of the Southeastern Conference, one of the top conferences in NCAA Football. The team plays its home games at the Vaught-Hemingway Stadium, where they have a perfect 2-0 record this season.

Key Players and Season Performance

Quarterbacks Trinidad Chambliss and Austin Simmons have played three games each this season. Chambliss has recorded 412 passing yards with 2 touchdowns, while Simmons leads with 580 passing yards and 4 touchdowns. Kewan Lacy is the standout running back, with 290 rushing yards and 5 touchdowns, ranking him 20th in rushing yards nationwide.

Impressive Team Stats and Betting Trends

The Rebels have scored 134 points this season, ranking them 13th overall. Defensively, they have allowed 65 points, placing them 50th, while their sack total of 4 ranks them 10th. Ole Miss is unbeaten in straight-up trends, spread trends, and over/under trends, all standing at 3-0 this season.

Tulane Green Wave: Unbeaten and Ready

The Tulane Green Wave are part of the American Conference. They have a perfect record of 3-0 this season. Last year, they played in the Union Home Mortgage Gasparilla Bowl but lost to the Florida Gators.

Quarterback Jake Retzlaff stands out with 522 passing yards and 2 touchdowns this season. Running back Javin Gordon leads the team with 122 rushing yards. Wide receiver Omari Hayes has made 13 receptions for 143 yards.

Tulane’s defense ranks 10th in sacks with 4 and 6th in interceptions with 5. They have allowed 61 points this season, ranking them 46th. Tulane is perfect in straight-up and against the spread trends, both at 3-0.

Final Betting Pick

Ole Miss is a solid pick for the money line at -434. They have a strong home record this season, winning both games at Vaught-Hemingway Stadium. Their high AP ranking at #13 indicates they are performing well, making them a reliable choice at home.

The over 61.5 is a good bet because both teams have shown they can score. Ole Miss has a high offensive rank, and the over has hit in all their games this season. With both teams having strong offenses, this game could see a lot of points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.