The San Francisco 49ers will face off against the Tampa Bay Buccaneers at 1:00 ET on Sunday, November 10th. This matchup is being played at Raymond James Stadium in Tampa Bay.

On the money line, the 49ers are -245 favorites as they head into their week 10 matchup against the Buccaneers. The 49ers are favored by -5.5 on the road, with the over/under line set at 51 points. The Buccaneers, the underdog at +204 on the money line, will host this NFC matchup at Raymond James Stadium in Tampa, FL. The game is set for 1:00 ET, and FOX will broadcast it. The 49ers and Buccaneers’ records need to be added.

• Date: Sunday, November 10th
• Time: 1:00 ET
• Location: Raymond James Stadium, Tampa Bay
• TV: FOX

49ers vs Buccaneers

After losing two straight, the 49ers bounced back in week 8 with a 30-24 win over the Cowboys, improving their record to 4-4. San Francisco was favored by 5.5 points and covered the spread, bringing their ATS record to 4-4. They have been favored in all of their games so far. Their O/U record stands at 5-3, with their games averaging 49 points compared to an average line of 46.2.

Heading into week 10, the 49ers rank 6th in our power rankings and have a 40.4% chance of making the playoffs and a 33.0% chance of winning the NFC West. They are 1-2 in division games and 2-3 in conference play. They are 3-2 at home and 1-2 on the road.

After a week 6 win over the Saints, the Buccaneers have now dropped three straight games, including a 30-24 loss to the Chiefs in week 9. Tampa Bay was able to cover the spread as 8.5-point underdogs, but the loss dropped them to 4-5 on the season. Despite their losing streak, the Bucs still rank 11th in our NFL power rankings and have a +1.8 scoring margin. Against the spread, they are 5-4, and their O/U record is 7-2, with the over hitting in six straight games.

Heading into week 10, Tampa Bay has a 40.8% chance of making the playoffs and a 19.7% chance of winning the NFC South. In division games, the Bucs are 1-2, but they are 4-2 against NFC opponents. Their 4-5 record puts them 2nd in the NFC South, and they are 2-3 at home and 2-2 on the road.

49ers Injury Report

• Javon Hargrave – Triceps (Out)
• Christian McCaffrey – Calf/achilles (Questionable)
• Jon Feliciano – Knee (Questionable)
• Kevin Givens – Groin (Questionable)
• Dre Greenlaw – Achilles (Out)
• Deebo Samuel Sr. – Ribs (Questionable)
• Brandon Aiyuk – Knee (Out)
• Jauan Jennings – Hip (Questionable)
• Yetur Gross-Matos – Knee (Out)
• Matthew Wright – Shoulder/back (Out)
• Curtis Robinson – Knee (Out)
• Talanoa Hufanga – Wrist (Out)
• Jordan Mason – Shoulder (Questionable)
• Drake Jackson – Knee (Out)
• Ambry Thomas – Forearm (Out)
• Elijah Mitchell – Hamstring (Out)
• Dee Winters – Concussion (Questionable)
• Renardo Green – Ankle (Questionable)
• Jake Moody – Right Ankle (Questionable)

Buccaneers Injury Report

• Evan Deckers – Hamstring (Questionable)
• Silas Dzansi – Knee (Out)
• Markees Watts – Quad (Out)
• Jalen McMillan – Hamstring (Questionable)
• SirVocea Dennis – Shoulder (Out)
• Kameron Johnson – Ankle (Out)
• Bryce Hall – Ankle (Out)
• Cody Thompson – Shoulder (Out)
• Jamel Dean – Hamstring (Out)
• Sua Opeta – Knee (Out)
• Greg Gaines – Calf (Questionable)
• Chase Edmonds – Knee (Out)
• Mike Evans – Hamstring (Out)
• Chris Godwin – Ankle (Out)

49ers Offense Breakdown

Heading into week 10, the 49ers are 10th in our offensive power rankings. They are 6th in the NFL in points per game, averaging 26.2, and 2nd in yards per game, with 412.4. Despite ranking 19th in passing attempts, they are 4th in passing yards per game, with 253.4. On the ground, they average 159 rushing yards per game, also 4th in the league, on 31 attempts per game.

In week 8, Brock Purdy threw for 260 yards and a touchdown, completing 18 of 26 passes without an interception. George Kittle led the team with 128 receiving yards on 6 catches, while Isaac Guerendo had 85 rushing yards and a touchdown. The 49ers scored 21 points in the 3rd quarter against Dallas and converted 50% of their 3rd downs.

Buccaneers Offense Breakdown

Heading into week 10, the Buccaneers are 7th in our offensive power rankings, averaging 28.8 points per game, which ranks 5th in the NFL. They also rank 5th in passing yards per game, with 250.8, on 35 attempts per game. Tampa Bay is 2nd in the NFL in 3rd-down conversion percentage, converting 51.8% of their attempts, and they rank 4th in red zone attempts, although they are 27th in red zone conversion percentage, at 8.8%.

In week 9, Baker Mayfield threw for 200 yards and 2 touchdowns, completing 23 of 31 passes without an interception. Cade Otton led the team in receiving, with 8 catches for 77 yards and a touchdown, while Bucky Irving had 24 rushing yards on 7 carries. Tampa Bay scored 10 points in the 3rd quarter and 7 in the 4th against the Chiefs, converting all 3 of their red zone opportunities.

49ers Team Defense

In their 30-24 win over the Cowboys, the 49ers’ defense allowed just 56 rushing yards on 19 attempts. Despite giving up 236 passing yards, including two touchdowns through the air, San Francisco defended the pass well, allowing just 2.9 yards per attempt. They also came away with two interceptions and limited Dallas to a 33.3% conversion rate on third down.

The 49ers’ defense pressured the quarterback throughout the game, coming away with two sacks and winning both the QB hit and tackles for loss differentials. The unit forced the Cowboys into a one-dimensional offense, as Dallas managed only 292 total yards against them.

Buccaneers Team Defense

In their 30-24 overtime loss to the Chiefs, the Buccaneers’ defense allowed three passing touchdowns and struggled to get off the field on third downs, allowing a 66.7% conversion rate. Despite pressuring the quarterback with four sacks and hitting the QB more than the Chiefs, Tampa Bay allowed Kansas City to complete 77.3% of their passes for 260 yards.

Tampa Bay’s run defense held up relatively well, allowing just 3.5 yards per attempt and 124 yards on 35 carries. However, the Bucs will look to improve defensively after allowing the Chiefs to convert on 10 of 13 third down attempts.

49ers vs Buccaneers Trends

• Across their three previous road games, San Francisco has an ATS mark of 1-2. Their straight up record in these matchups was 1-2 while averaging 25 points per game.
• When looking at their past ten home matchups, Tampa Bay has an ATS record of 7-3 while averaging 25 per game. The team went 5-5 overall in these games.
• In their last ten games as the betting underdog, the Buccaneers have a straight up record of 5-5 and an ATS mark of 6-4.
• Spanning across their last ten games as the betting favorite, the 49ers have gone 4-6 vs the spread. Their overall record in these games was 5-5.

49ers vs Buccaneers Prediction

Our pick vs. the spread is to take the 49ers to cover as road favorites in their week 10 matchup against the Buccaneers. The point spread lines have the 49ers at -5.5, and we have them winning by a score of 31-25.

For an over/under pick, we are leaning towards taking the over, with a projected combined score of 56 points and the O/U line sitting at 51 points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.