Arizona Cardinals vs Los Angeles Rams NFL Betting Prediction

NFL Cardinals vs Los Angeles Rams Prediction 12/28/2024

The Arizona Cardinals will face off against the Los Angeles Rams at 8:00 ET on Saturday, December 28th. This matchup is being played at SoFi Stadium in Inglewood.

The Rams are favored at -273 on the money line as they host the Cardinals in week 17 NFC West matchup. The game, which kicks off at 8:00 ET on Saturday, December 28th at SoFi Stadium in Inglewood, CA, will be broadcast on NFLN. The Cardinals are +222 on the money line, and the Rams are -6 point favorites with an over/under line of 48 points.

  • Date: Saturday, December 28th
  • Time: 8:00 ET
  • Location: SoFi Stadium, Inglewood
  • TV: NFLN

Cardinals vs Rams

arizona cardinals nfl

With a 7-8 record, the Cardinals are 3rd in the NFC West and 17th in our power rankings. They have a +0.1 scoring margin and are 9-6 against the spread, including a 6-2 mark as underdogs. Their O/U record is 7-7-1, with the over hitting in three straight games.

Arizona’s playoff chances are down to 0.0% after their week 16 loss to the Panthers. The Cardinals were 5.5-point favorites but couldn’t get the win, dropping their record to 7-8. They were coming off a week 15 win over the Patriots, where they covered the spread with a 13-point victory.

With four straight wins, the Rams are now 9-6 and sit atop the NFC West. After a week 12 loss to the Eagles, LA bounced back with victories over the Saints, Bills, 49ers, and Jets. In week 16, they defeated New York 19-9, covering the 3-point spread. This puts their ATS record at 8-7, with four consecutive covers.

Our projections give the Rams an 81.2% chance of making the playoffs and winning the division. They rank 12th in our power rankings. Their O/U record is 7-8, with the under hitting in their last two games.

Cardinals Injury Report

  • Matt Prater – Left Knee (Questionable)
  • Angelo Blackson – Undisclosed (Out)
  • James Conner – Knee (Questionable)
  • Will Hernandez – Knee (Out)
  • Justin Jones – Triceps (Out)
  • Bilal Nichols – Stinger (Out)
  • Dennis Gardeck – Knee (Out)
  • Jonah Williams – Knee (Questionable)
  • Mack Wilson Sr. – Concussion (Questionable)
  • Markus Bailey – Suspension (Out)
  • Carter O’Donnell – Undisclosed (Out)
  • Blake Gillikin – Right Foot (Out)
  • Baron Browning – Neck (Questionable)
  • Jesse Luketa – Thigh (Out)
  • Joey Blount – Ribs (Questionable)
  • BJ Ojulari – Knee (Out)
  • Paris Johnson Jr. – Knee (Questionable)
  • Trey Benson – Ankle (Questionable)
  • Emari Demercado – Back (Out)
  • Elijah Jones – Heel (Questionable)

Rams Injury Report

  • KT Leveston – Ankle (Out)
  • Derion Kendrick – Knee (Out)
  • Tre Tomlinson – Undisclosed (Out)
  • Nick Hampton – Pectoral (Out)
  • Larrell Murchison – Foot (Out)
  • Troy Reeder – Hamstring (Out)
  • John Johnson III – Shoulder (Out)
  • Conor McDermott – Undisclosed (Out)

Cardinals Offense Breakdown

Heading into week 17, the Cardinals rank 12th in our offensive power rankings. They are 14th in the NFL in scoring, averaging 22.9 points per game, and 11th in total offense with 353.4 yards per game. Arizona has leaned on their run game, ranking 5th in the league with 145.8 rushing yards per contest. On 3rd down, they have converted 43.2% of their attempts, which ranks 8th in the NFL.

In week 16, the Cardinals scored 30 points in a loss to the Panthers, with 17 of those coming in the 2nd quarter. Kyler Murray threw for 202 yards, completing 20 of 32 passes, with 1 touchdown and 1 interception. James Conner rushed for 117 yards on 15 carries and also led the team in receiving with 4 catches for 49 yards.

Rams Offense Breakdown

los angeles rams

Heading into week 17, the Rams are 11th in our offensive power rankings. They are 17th in the NFL in points per game (21.9) and 15th in yards per game (331.5). Los Angeles ranks 13th in passing yards per game (224) and 20th in rushing yards per game (107.5). They are 23rd in the league in 3rd-down conversion percentage (36.6%) and 22nd in red zone conversion percentage, despite ranking 6th in red zone attempts. The Rams have struggled early in games, ranking 23rd in 1st-quarter scoring.

Matthew Stafford threw for 110 yards (14/19) with 1 touchdown and 1 interception in week 16 against the Jets. He was not sacked in the game. Kyren Williams rushed for 122 yards on 23 carries, and Puka Nacua had 8 receptions for 56 yards. The Rams scored 13 points in the 4th quarter after being shut out in the 1st and 3rd quarters.

Cardinals Team Defense

In their most recent game, the Cardinals lost to the Panthers 36-30 in overtime. The Arizona defense gave up 243 rushing yards on just 36 attempts, with Carolina averaging 6.8 yards per attempt. Despite this, the Cardinals held the Panthers to 149 passing yards on 17 completions. However, they did allow two passing touchdowns.

Arizona’s defense managed three sacks in the game and held Carolina to a 42.9% third-down conversion rate. The Cardinals’ run defense will need to improve after this performance.

Rams Team Defense

The Rams’ defense gave up 246 passing yards to the Jets in their most recent game, but they still came out on top with a 19-9 win. The Jets managed to convert on 38.5% of their third down attempts and had one passing touchdown. Los Angeles defended the run well, allowing just 75 rushing yards on 20 attempts.

Overall, the Rams allowed 321 total yards and 28 completions. They recorded one sack and one tackle for loss less than the Jets.

Cardinals vs Rams Trends

  • Across their three previous road games, Arizona has an ATS mark of 1-2. Their straight up record in these matchups was 0-3 while averaging 19 points per game.
  • Across their last five home contests, Los Angeles has been good against the spread posting a mark of 5-0. Their overall mark in these games was 5-0, while averaging 21 points per game.
  • Through their last five games as the underdog, the Cardinals have an ATS record of 4-1 and a straight up mark of 3-2.
  • Through their last five games as the favorite, the Rams have an ATS record of 4-1 and a straight up mark of 4-1.

Cardinals vs Rams Prediction

Our pick vs. the spread is to take the Cardinals to cover as road underdogs in this week 17 matchup between the Rams and Cardinals. Even though the point spread has the Cardinals at +6, we have the Rams winning 22-20, making the Cardinals our pick to cover.

As for the over/under, with the line sitting at 48 points, we are leaning towards taking the under, with our projections pointing to a combined score of 42 points.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.