Buffalo Bills vs Tampa Bay Buccaneers NFL Betting Prediction

NFL Buffalo Bills vs Tampa Bay Buccaneers Prediction 8/23

The Buffalo Bills will play the Tampa Bay Buccaneers on Saturday, August 23, 2025. The game will take place at Raymond James Stadium in Tampa Bay, FL, with a start time of 7:30 PM. Fans can tune in to NFLN to watch the game, which is set to be played under clear skies with a light breeze. The Bills are looking for their first preseason win, while the Buccaneers aim to continue their winning streak.

Bills vs. Buccaneers Betting Prediction

  • Money Line Prediction: Buccaneers +112. The Buccaneers are playing at home and have won both preseason games so far. The Bills have lost both of their preseason games, making the Buccaneers a better value pick.
  • Over/Under Prediction: Under 37.5. The Bills have struggled to score in the preseason, and the Buccaneers have a strong defense, allowing only 21 points over two games.

Team Trends

  • The Buffalo Bills lost their last preseason game against the Chicago Bears, 38-0.
  • In the previous regular season, the Buffalo Bills had an 8-0 home record.
  • The Tampa Bay Buccaneers have a 2-0 record in this preseason.
  • The Buccaneers won their last home preseason game against the Tennessee Titans, 29-7.
  • The game will be held at Raymond James Stadium with a clear sky forecast.

Bills vs Buccaneers Preview

The Buffalo Bills are set to visit the Tampa Bay Buccaneers in Week 3 of the 2025 preseason. The Bills have yet to find their rhythm, standing at 0-2 in the preseason. They aim to turn things around at Raymond James Stadium. The Buccaneers, on the other hand, have started strong with a 2-0 record. They are looking to maintain their momentum at home.

Mitchell Trubisky is expected to lead the Bills’ offense, with a projected 55 passing yards. Meanwhile, Frank Gore Jr. could be a key player in the backfield. For the Buccaneers, Teddy Bridgewater is projected to pass for 85 yards and two touchdowns. Bucky Irving is also set to make an impact with his rushing game. This game will provide both teams with a chance to evaluate their depth and make necessary adjustments before the regular season.

Tampa Bay Buccaneers: Preseason Highlights

The Tampa Bay Buccaneers, led by head coach Todd Bowles, are having a strong preseason. They have a perfect 2-0 record. Last season, they finished 10-7, which placed them in the NFC South division.

In the quarterback position, Teddy Bridgewater is projected to lead with 85 passing yards and two touchdowns. Connor Bazelak follows with 106 passing yards. Kyle Trask is also expected to contribute with 19 passing yards.

Bucky Irving is the top running back with 12 rushing yards and one reception. In the wide receiver group, Emeka Egbuka is leading with 5 receiving yards and one touchdown. The Buccaneers’ defense is also performing well with six sacks this preseason.

Buffalo Bills: Ready for a New Challenge

The Buffalo Bills have Sean McDermott as their head coach. Last season, they had a 13-4 record and placed well in the AFC East. This preseason, they have not won yet, with a 0-2 record.

Mitchell Trubisky is projected to lead the quarterback lineup. He is expected to throw for 55 yards in this game. Mike White is right behind him with 54 passing yards projected.

Frank Gore Jr. is the top running back with 51 rushing yards projected. Tyrell Shavers leads the wide receivers with 29 receiving yards expected. The Bills’ defense is ranked 7th in sacks this preseason.

Final Betting Pick

The Buccaneers are a solid pick for the money line at +112. They have played well in the preseason, winning both games. Playing at home gives them an advantage, and their defense has been strong, allowing only 21 points in two games.

The under 37.5 is a good choice because the Bills have struggled to score in the preseason. They have only managed 25 points in two games. The Buccaneers’ defense ranks second in opponent scores, which supports the under prediction.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.