The New Orleans Saints will play against the Seattle Seahawks on Sunday, September 21, 2025. The game will take place at Lumen Field in Seattle, WA, at 4:05 PM. Fans can catch the action on CBS.

Saints vs. Seahawks Betting Prediction

• Money Line Prediction: Seattle Seahawks -391. The Seahawks have a stronger offense and are playing at home. The Saints have struggled this season with an 0-2 record.
• Over/Under Prediction: Under 41.5. The Saints have not scored more than 21 points in a game this season, and the Seahawks’ defense ranks 11th in opponent scoring.

Team Trends

• The Seattle Seahawks have a season record of 1-1-0 and have not won a home game yet this season.
• The New Orleans Saints are still looking for their first win of the season with a record of 0-2-0.
• In their last game, the Seahawks won against the Pittsburgh Steelers with a score of 31-17.
• The Saints lost their last game against the San Francisco 49ers with a score of 26-21.
• Seattle’s head coach is Mike Macdonald, while the Saints’ head coach is Kellen Moore.

Saints vs Seahawks Preview

The New Orleans Saints are looking for their first win of the season as they travel to face the Seattle Seahawks. With a 0-2 record, the Saints hope to turn things around at Lumen Field. Quarterback Spencer Rattler is expected to lead the charge with 197 passing yards and a touchdown. Alvin Kamara will be key in the run game, projected to gain over 60 yards.

The Seahawks, with a 1-1 record, aim to secure a win at home. Sam Darnold is set to throw for 246 yards and 1.5 touchdowns. The wide receiver duo of Jaxon Smith-Njigba and Cooper Kupp will be vital, combining for over 130 receiving yards. Both teams are eager to improve their standings in the NFC.

Seattle Seahawks: Home Team Overview

The Seattle Seahawks are led by Head Coach Mike Macdonald. They play in the NFC West division and call Lumen Field their home. This season, the Seahawks have a record of 1-1, with a home record of 0-1.

Sam Darnold is the top quarterback for the Seahawks. He has played in two games this season, throwing for 445 passing yards and two touchdowns. Kenneth Walker III is a standout running back, with 125 rushing yards and one touchdown in two games.

Jaxon Smith-Njigba is the leading wide receiver with 227 receiving yards over two games. The team ranked 8th in passing yards last season. On defense, they ranked 6th in sacks, showcasing a strong defensive front.

New Orleans Saints: Away Team Analysis

The New Orleans Saints are guided by Head Coach Kellen Moore. They play in the NFC South and have a current season record of 0-2. The Saints’ home record is also 0-2, with all games played at Caesars Superdome.

Spencer Rattler stands as the top quarterback, having thrown for 421 passing yards in two games. He has achieved three passing touchdowns without any interceptions. In this upcoming game, Rattler is projected to add 197 passing yards and one touchdown.

Alvin Kamara is a key player for the Saints, with 144 rushing yards and one rushing touchdown so far. He is expected to contribute 62.1 rushing yards and 0.4 rushing touchdowns in this game. Chris Olave leads the wide receivers with 108 receiving yards, and he is projected to catch 65.8 receiving yards.

Final Betting Pick

The Seattle Seahawks are favored with a money line of -391. They have a stronger offense, ranking 8th in passing yards last season. Playing at home in Lumen Field gives them an edge, as they aim to improve their home record. Sam Darnold is projected to throw for 246.2 yards, which can challenge the Saints’ defense.

The over/under is set at 41.5, with a prediction for the total to go under. The Saints have struggled to score, not surpassing 21 points in any game this season. The Seahawks’ defense ranks 11th in opponent scoring, which can limit the Saints’ offense. This makes the under a solid choice for this game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.