The Tennessee Titans will face off against the Indianapolis Colts at 1:00 ET on Sunday, December 22nd. This matchup is being played at Lucas Oil Stadium in Indianapolis.

The Colts are favored at -4.5 as they host the Titans at Lucas Oil Stadium in Indianapolis. The Colts’ money line odds are -218, while the Titans are at +180. This week 16 AFC South matchup is set for 1:00 ET, and the over/under line is at 42.5 points. On the TV side, this one is on CBS.

• Date: Sunday, December 22nd
• Time: 1:00 ET
• Location: Lucas Oil Stadium, Indianapolis
• TV: CBS

Titans vs Colts

With a 3-11 record, the Titans are currently on a three-game losing streak, including a 37-27 loss to the Bengals in week 15. This puts them in 4th place in the AFC South, and our power rankings have them 28th heading into week 16. Tennessee has a -8.9 scoring margin this season and is 2-12 against the spread. They are 0-4 ATS as favorites and 2-8 as underdogs.

The Titans have a 8-5-1 O/U record, with their games averaging 45.2 points compared to an average line of 41.2. In week 15, they and the Bengals combined for 64 points, going over the 46-point line. In week 14, Tennessee and Jacksonville combined for just 16 points, well below the 40.5-point line.

Heading into week 16 with a 6-8 record, the Colts have an 8.7% chance of making the playoffs and rank 23rd in our power rankings. After a narrow win over the Patriots in week 13, they couldn’t keep the momentum going, losing 31-13 to the Broncos in week 15. Indianapolis was a 4.5-point underdog in that game but failed to cover the spread, bringing their ATS record to 8-6 this season.

The Colts have an average scoring margin of -3.5 points per game and are 7-7 on over/unders. Their games have averaged 43.5 points, just under their average line of 44.4. The over has hit in two straight games.

Titans Injury Report

• Quandre Diggs – Lisfranc Injury (Out)
• Garret Wallow – Pectoral (Out)
• Treylon Burks – Knee (Out)
• L’Jarius Sneed – Quad (Out)
• Lloyd Cushenberry III – Achilles (Out)
• Marlon Davidson – Bicep (Out)
• Luke Gifford – Concussion (Questionable)
• Otis Reese IV – Ankle (Questionable)
• Jaelyn Duncan – Hamstring (Questionable)
• Colton Dowell – Knee (Questionable)
• TK McLendon Jr. – Toe (Out)
• Chance Campbell – Knee (Out)
• Roger McCreary – Shoulder (Questionable)
• Logan Bruss – Knee (acl) (Out)
• Andrew Rupcich – Triceps (Out)
• Jack Gibbens – Lower Leg (Out)
• Julius Wood – Suspended (Out)

Colts Injury Report

• Ryan Coll – Undisclosed (Out)
• Jaylon Carlies – Ankle (Questionable)
• Jelani Woods – Toe (Out)
• Daniel Scott – Achilles (Out)
• Trevor Denbow – Knee (Out)
• Wesley French – Ankle (Out)
• JuJu Brents – Knee (Out)
• Alec Pierce – Concussion (Questionable)
• Will Fries – Tibia (Out)
• Juwann Winfree – Undisclosed (Out)
• Ashton Dulin – Ankle (Questionable)
• Ryan Kelly – Calf (Questionable)
• Samson Ebukam – Achilles (Out)
• Trysten Hill – Undisclosed (Out)
• Braden Smith – Personal (Out)

Titans Offense Breakdown

Heading into week 16, the Titans rank 30th in our offensive power rankings. They are 24th in the NFL in points per game, averaging 18.1, and 26th in passing yards per game with 190.6. Tennessee is 19th in passing attempts per game and 18th in rushing attempts, averaging 110.4 rushing yards per game. On third downs, they rank 22nd with a 36.6% conversion rate, but they have been strong in the red zone, converting 39.5% of their attempts, which ranks 8th in the league.

In week 15, the Titans scored 27 points against the Bengals, with 14 coming in the first quarter and 13 in the fourth. Mason Rudolph threw for 209 yards, completing 21 of 26 passes with 2 touchdowns and 1 interception. Tony Pollard had 45 rushing yards on 17 carries, while Tyjae Spears led the team in receiving with 6 catches for 87 yards and a touchdown.

Colts Offense Breakdown

Indianapolis ranks 28th in our offensive power rankings, averaging 20 points per game and 311.4 yards per game, both 20th in the NFL. They are 23rd in passing attempts, with 190.4 passing yards per game, ranking 27th. On the ground, they average 27.1 rushing attempts (13th) and 120.9 rushing yards per game (12th). The Colts are 24th in 3rd-down conversions, with a 35.8% success rate, but they are 12th in red zone conversion percentage.

Anthony Richardson struggled in week 15, posting a passer rating of 36, with 172 yards on 17/38 passing and 2 interceptions. Jonathan Taylor rushed for 107 yards on 22 carries, while Michael Pittman Jr. had 6 catches for 58 yards. The Colts scored 13 points against Denver, all in the first half, and converted only 4 of 15 3rd-down attempts without a red zone touchdown.

Titans Team Defense

In their 37-27 loss to the Bengals, the Titans’ defense struggled on third downs, allowing the Bengals to convert 76.9% of their third down attempts. Despite this, they did manage to force two interceptions. The Titans allowed the Bengals to complete 70.3% of their passes for 269 yards, with three passing touchdowns. They also gave up 101 rushing yards on 26 attempts.

Tennessee’s defense managed just one sack in the game and allowed the Bengals to hit on big plays, resulting in 7.3 yards per passing attempt. Additionally, the Titans lost the tackles for loss differential by -4.

Colts Team Defense

In their 31-13 loss to the Broncos, the Colts’ defense allowed just 121 passing yards but gave up three passing touchdowns. They struggled to generate pressure, finishing with only one sack and losing the QB hit differential by nine. Despite their struggles against the pass, they did force three interceptions.

Against the run, the Colts were solid, allowing just 72 yards on 27 attempts. However, their inability to disrupt the backfield and pressure the quarterback contributed to their overall defensive struggles in the game.

Titans vs Colts Trends

• Through their last three road contests, the Titans offense has averaged 22 points per game while allowing an average of 32. Tennessee posted an overall record of 1-2 while going 1-2 ATS.
• In their last five games at home, the Colts have a straight up record of 2-3 while going 2-3 vs the spread. The team’s offense averaged 19 points per game in these contests.
• Going back to their previous three games as the underdog, Tennessee has an ATS mark of 1-2 while going 1-2 straight up.
• Indianapolis has done well both straight up and vs the spread when favored to win the game, going 3-0 SU and 3-0 ATS in their last three games.

Titans vs Colts Prediction

Our prediction for this week 16 matchup between the Colts and Titans is that the Colts will come out on top by a score of 25-16. With the point spread sitting at 4.5 points in favor of the Titans, we like the Colts to cover as home favorites.

For this game, we also have a pick against the over/under line. Currently, the O/U line is at 42.5 points, and we are leaning towards taking the under, with a projected combined score of 41 points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.