The Arizona Diamondbacks will take on the San Diego Padres on Saturday, September 27, 2025, at 8:40 PM. The game will be held at PETCO Park in San Diego, CA. Fans can expect a warm evening with a light breeze and few clouds as they tune in on SDPA to watch the action unfold.

Diamondbacks vs. Padres Betting Prediction

• Money Line Prediction: San Diego Padres -141. The Padres have a strong home record of 50-29 and recently won against the Diamondbacks. Their starting pitcher, Michael King, has a better ERA than Eduardo Rodriguez of the Diamondbacks.
• Over/Under Prediction: Over 7.5 (-117). Both teams have shown the ability to score runs, with the Padres scoring 7 in their last game against the Diamondbacks. The Diamondbacks have also allowed a fair number of runs in recent games.

Team Trends

• The Arizona Diamondbacks have a road record of 37-42 this season.
• The San Diego Padres have a strong home record of 50-29 this season.
• Arizona’s current streak is three losses, with a recent 7-4 loss to the Padres.
• San Diego is on a winning streak, having won their last game against Arizona 7-4.
• Fernando Tatis Jr. contributed significantly to the Padres’ recent win with a home run and four RBIs.

Diamondbacks vs Padres Preview

The Arizona Diamondbacks will visit the San Diego Padres at PETCO Park on September 27, 2025. The Diamondbacks hold a record of 80-80, sitting in third place in the division. They have struggled recently, losing their last three games. Eduardo Rodriguez will take the mound for Arizona. He has a 9-8 record with a 4.91 ERA and a 1.56 WHIP.

The Padres, with an 88-72 record, are second in the division. They have won six of their last ten games. Michael King will pitch for San Diego. He has a 5-3 record, a 3.57 ERA, and a 1.20 WHIP. Fans can watch the game on SDPA as these teams meet under the lights in San Diego.

San Diego Padres: Key Players and Stats

Manny Machado leads the Padres with 26 home runs, ranking 17th in the league. He has played 158 games, showing his durability. His batting average is .272, making him a consistent hitter. Luis Arraez has a batting average of .292, the highest on the team. He has played 153 games and contributed 65 runs. His on-base percentage is .328, providing a steady presence at the plate. Michael King will start as the pitcher for the Padres. His ERA is 3.57, which is solid for the team. King’s WHIP is 1.20, indicating his control on the mound.

Arizona Diamondbacks: Key Players and Stats

Geraldo Perdomo stands out for the Diamondbacks. He has played 159 games with a batting average of .291. Perdomo leads the team with 97 runs and 98 RBIs. Ketel Marte has been a strong performer as well. He has 27 home runs, the most on the team. Marte’s batting average is .283 over 125 games. Gabriel Moreno adds depth to the lineup. He has a batting average of .282 in 81 games. Moreno has contributed 44 runs and 40 RBIs this season.

Final Betting Pick

The Padres have a strong home record of 50-29, making them a solid pick for the money line at -141. Michael King, the Padres’ starting pitcher, has a better ERA of 3.57 compared to Eduardo Rodriguez’s 4.91. This pitching advantage adds confidence to the Padres’ chances at home.

For the over/under prediction, choosing over 7.5 runs seems reasonable. The Padres scored 7 runs in their last game against the Diamondbacks, indicating their ability to score. The Diamondbacks have also allowed a fair number of runs recently, which supports the over prediction. Both teams have shown they can contribute to a higher-scoring game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.