Arizona Diamondbacks vs San Diego Padres MLB Betting Prediction

MLB Arizona Diamondbacks vs San Diego Padres Prediction 9/28

The Arizona Diamondbacks will take on the San Diego Padres at PETCO Park on Sunday, September 28, 2025, at 3:10 PM. The Diamondbacks have a record of 80-81 and are ranked 4th in their division. The Padres hold a record of 89-72 and are 2nd in the division. The weather forecast predicts a mild day with scattered clouds, and the game will be aired on ARID.

Diamondbacks vs. Padres Betting Prediction

  • Money Line Prediction: San Diego Padres -114. The Padres have a strong home record of 51-29 and are on a 2-game winning streak. They have also won 7 of their last 10 games, making them a solid choice.
  • Over/Under Prediction: Over 8.0 (-105). Both starting pitchers have ERAs over 5.00, and the Padres have been scoring well in recent games, suggesting a higher-scoring game.

Team Trends

  • The San Diego Padres have a strong home record this season with 51 wins and 29 losses.
  • The Arizona Diamondbacks have struggled on the road, with a record of 37 wins and 43 losses.
  • The Padres are on a 2-game winning streak, while the Diamondbacks have lost their last 4 games.
  • In their recent game on September 27th, the Padres defeated the Diamondbacks with a score of 5-1.
  • The weather forecast for the game day is mild with scattered clouds and calm wind.

Diamondbacks vs Padres Preview

The Arizona Diamondbacks are set to compete against the San Diego Padres at PETCO Park. Arizona enters the game with an 80-81 record, currently on a four-game losing streak. Their recent performance shows a 4-6 record over the last ten games. Brandon Pfaadt will take the mound for the Diamondbacks. He has a 5.00 ERA and a WHIP of 1.33, with a season record of 13-8.

The San Diego Padres, holding an 89-72 record, aim to extend their two-game winning streak. They have been strong lately, winning seven of their last ten games. JP Sears will start for the Padres. Sears has a 5.12 ERA and a WHIP of 1.30, with an 8-11 record this season. Fans can catch the game on ARID, and the weather forecast predicts a mild day with scattered clouds.

San Diego Padres: Home Team Insights

The San Diego Padres have a strong lineup this season. Manny Machado leads the team in home runs, runs, and RBIs. He has 26 home runs, 89 runs, and 93 RBIs, making him a key player. Luis Arraez is another important hitter for the Padres. He has a batting average of .292 and has played in 154 games. His 66 runs put him second on the team. On the pitching side, JP Sears will start for the Padres. He has an ERA of 5.12 and a WHIP of 1.30. His win-loss record stands at 8-11.

Arizona Diamondbacks: Away Team Overview

The Arizona Diamondbacks have some strong hitters in their lineup. Geraldo Perdomo is a standout player, leading the team with 98 runs and 99 RBIs. He also has a batting average of .291 and has played in 160 games. Ketel Marte adds power to the Diamondbacks with 27 home runs. He has a batting average of .283 and has scored 86 runs. Marte ranks first on the team in home runs. On the mound, Brandon Pfaadt will start for the Diamondbacks. His ERA is 5.00, with a WHIP of 1.33. Pfaadt has a win-loss record of 13-8 this season.

Final Betting Pick

The San Diego Padres are a strong pick for the money line at -114. They have a solid home record of 51-29 and are on a 2-game winning streak. Winning 7 of their last 10 games shows they are in good form.

The over 8.0 prediction is also a good choice. Both starting pitchers have ERAs over 5.00, which suggests they might give up runs. The Padres have been scoring well, as seen in their recent games, which supports the idea of a high-scoring game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.