Athletics vs Pittsburgh Pirates MLB Betting Prediction
PublishedSeptember 21, 2025,            Posted By: Maria Uebelhor
Last updated:September 21, 2025 ,

MLB Athletics vs Pittsburgh Pirates Prediction 9/21

The Athletics will play the Pittsburgh Pirates on Sunday, September 21, 2025, at PNC Park. The game starts at 1:35 PM, and fans can watch it on NSPCA. The weather forecast predicts a mild day with a light breeze and scattered clouds. The Athletics hold a record of 73-82, while the Pirates stand at 66-89.

Athletics vs. Pirates Betting Prediction

  • Money Line Prediction: Athletics -107. The Athletics have a better recent record, going 7-3 in their last 10 games, while the Pirates have struggled at 2-8. The Athletics also have a balanced road record of 40-40, making them a solid choice.
  • Over/Under Prediction: Under 8.5 (-104). Both teams have shown limited scoring in recent games, with the Athletics scoring only 4 runs in their last two games and the Pirates scoring 2 runs in their last game. The starting pitchers have respectable ERAs, suggesting a low-scoring game.

Team Trends

  • The Athletics have a balanced road record of 40-40 this season.
  • In their last game, the Pirates won 2-0 against the Athletics, with Bubba Chandler pitching 5 scoreless innings.
  • The Pirates have a better home record at 43-37 compared to their overall season performance.
  • The Athletics have won 7 of their last 10 games, showing strong recent form.
  • The Pirates have struggled in their last 10 games, winning only 2 of them.

Athletics vs Pirates Preview

The Athletics and Pirates are set to meet at PNC Park. The Athletics have a 73-82 record, placing them fourth in their division. They have been playing well recently, winning seven of their last ten games. Mitch Spence will take the mound for the Athletics. He has a 4.48 ERA and a 1.33 WHIP.

The Pirates, with a 66-89 record, are fifth in their division. They have struggled recently, winning only two of their last ten games. Mike Burrows will be their starting pitcher. Burrows has a 4.10 ERA and a 1.24 WHIP. Fans can expect an interesting game as these two teams compete.

Pirates’ Key Players and Stats

The Pittsburgh Pirates have some notable players on their roster. Andrew McCutchen leads the team in home runs with 13, runs with 49, and RBIs with 56. He has played 130 games this season with a batting average of .240. Spencer Horwitz is another key player for the Pirates. He has a batting average of .259 and has hit 9 home runs. Horwitz has also contributed 49 runs and 43 RBIs in 101 games. Jared Triolo has played 101 games this season. He has a batting average of .223, with 6 home runs and 38 runs scored. Triolo also has 21 RBIs, making him a valuable player for the team.

Athletics Ready for Action

The Oakland Athletics have a strong lineup. Nick Kurtz stands out with a batting average of .291. He has hit 33 home runs and scored 83 runs in 110 games. Kurtz also has 81 RBIs, leading the team in these categories. Shea Langeliers contributes with 30 home runs. He has played 118 games this season. Langeliers has a batting average of .259 and has scored 69 runs. Jacob Wilson is another key player for the Athletics. He has a batting average of .318. Wilson has played 119 games, hitting 13 home runs and scoring 60 runs.

Final Betting Pick

 

The Athletics have been strong on the road with a balanced 40-40 record. They have also won 7 of their last 10 games, showing they can perform well away from home. The Pirates, on the other hand, have been struggling with a 2-8 record in their last 10 games.

For the Over/Under prediction, both teams have had limited scoring recently. The Athletics scored only 4 runs in their last two games, while the Pirates managed just 2 runs in their last game. With starting pitchers Mitch Spence and Mike Burrows having respectable ERAs, a low-scoring game seems likely.

 

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.