The Baltimore Orioles will play against the Chicago White Sox on Tuesday, September 16, 2025, at 7:40 PM. The game will take place at Rate Field in Chicago, IL. Fans can expect a warm evening with a light breeze and few clouds. Tune in to CHSN to catch the action.

Orioles vs. White Sox Betting Prediction

• Money Line Prediction: Baltimore Orioles +106. The Orioles have a better recent record, going 6-4 in their last 10 games, while the White Sox are on a 4-game losing streak. Baltimore also won the last game against Chicago, which gives them momentum.
• Over/Under Prediction: Under 8.0 (-115). Both teams have shown limited offensive production recently, with the last game ending with a total of 5 runs. The starting pitchers, Kremer and Smith, have decent ERAs, suggesting a low-scoring game.

Team Trends

• The Baltimore Orioles have a road record of 34-42 this season.
• The Chicago White Sox have a home record of 32-44 this season.
• Baltimore Orioles’ interim manager is Tony Mansolino.
• The Chicago White Sox are on a four-game losing streak.
• The game will be played at Rate Field in Chicago, IL.

Orioles vs White Sox Preview

The Baltimore Orioles are set to take on the Chicago White Sox in an evening game at Rate Field. With a record of 70-80, the Orioles are looking to build on their recent win. Dean Kremer will be on the mound for Baltimore. Kremer has a 4.43 ERA and a WHIP of 1.26 this season. His performance will be key as the Orioles aim to improve their standing in the division.

On the other side, the Chicago White Sox have struggled with a 57-94 record. They are on a four-game losing streak and hope to turn things around. Shane Smith will pitch for the White Sox. Smith holds a 3.78 ERA and a WHIP of 1.18. Fans can catch the game on CHSN and enjoy a warm evening with a light breeze in Chicago.

White Sox Home Field Insight

The Chicago White Sox have some strong hitters on their roster. Lenyn Sosa leads the team with 20 home runs and a .260 batting average. His performance has been key for the White Sox this season. Miguel Vargas has played in 128 games, hitting 14 home runs. He leads the team in runs with 71. Vargas’s consistency makes him a player to watch. Shane Smith will start on the mound for the White Sox. His ERA is 3.78, and he has a WHIP of 1.18. Smith’s pitching could be a deciding factor in the game.

Baltimore Orioles: Key Players and Pitching

Gunnar Henderson is a leading hitter for the Orioles. He has played in 142 games and has a .269 batting average. Henderson also leads the team in runs with 81 and RBIs with 62. Jackson Holliday is another strong player for Baltimore. He has hit 17 home runs in 140 games. His .255 batting average and 68 runs make him a key player. Dean Kremer will be the starting pitcher for the Orioles. His ERA is 4.43, and he has a WHIP of 1.26. Kremer’s performance on the mound could impact the game’s outcome.

Final Betting Pick

The Orioles are a strong pick for the money line at +106. They have a 6-4 record in their last 10 games, showing they are playing well. The White Sox, on the other hand, are struggling with a 4-game losing streak. Baltimore’s recent win against Chicago adds to their confidence, especially on the road.

For the over/under, taking the under 8.0 at -115 seems wise. Both teams have not been scoring much lately, with the last game ending 4-1. The starting pitchers, Kremer and Smith, have ERAs of 4.43 and 3.78, respectively. This suggests that runs might be limited in this game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.