Boston Red Sox vs Arizona Diamondbacks MLB Betting Prediction
PublishedSeptember 6, 2025,            Posted By: Maria Uebelhor
Last updated:September 6, 2025 ,

MLB Boston Red Sox vs Arizona Diamondbacks Prediction 9/6

The Boston Red Sox will play against the Arizona Diamondbacks on Saturday, September 6, 2025. The game will take place at Chase Field in Phoenix, AZ, and is scheduled to start at 8:10 PM. The Red Sox have a record of 78-64, while the Diamondbacks hold a 71-71 record. The game will be broadcast on NESN.

Red Sox vs. Diamondbacks Betting Prediction

  • Money Line Prediction: Arizona Diamondbacks -102. The Diamondbacks have a strong home record of 37-33 and are on a three-game win streak. Brandon Pfaadt, despite a higher ERA, has a solid win-loss record, which could give Arizona an edge.
  • Over/Under Prediction: Over 9.0 (-105). Both teams have shown they can score, with the Diamondbacks winning 10-5 in their last game against the Red Sox. The Red Sox also have a capable offense, making the over a good choice.

Team Trends

  • The Boston Red Sox have a road record of 34-36 this season.
  • The Arizona Diamondbacks hold a home record of 37-33 this season.
  • In their last game on September 5th, 2025, the Arizona Diamondbacks won against the Boston Red Sox 10-5.
  • Boston Red Sox manager is Alex Cora, and their pitching coach is Andrew Bailey.
  • Arizona Diamondbacks manager is Torey Lovullo, and their pitching coach is Brian Kaplan.

Red Sox vs Diamondbacks Preview

The Boston Red Sox head to Chase Field to face the Arizona Diamondbacks on Saturday night. Boston holds a record of 78-64 and is third in their division. They have lost their last two games but managed a 6-4 record in their last ten. Lucas Giolito will start on the mound for the Red Sox, with a solid 3.38 ERA and a 10-2 win-loss record.

The Arizona Diamondbacks, with a 71-71 record, are fourth in their division. They are on a three-game winning streak and have gone 7-3 in their last ten games. Brandon Pfaadt will pitch for Arizona, holding a 5.33 ERA and a 12-8 record. The game will be played under a retractable roof, so the weather should not affect play.

Diamondbacks Ready for Action

The Arizona Diamondbacks have some strong hitters this season. Geraldo Perdomo leads the team with 88 runs and 90 RBIs. Ketel Marte follows closely with a .288 batting average and 25 home runs. The team’s batting average stands at .250, placing them 8th in the league. Their slugging percentage is 2nd, showing their power at the plate. They have hit 197 home runs, ranking 4th overall. On the mound, Brandon Pfaadt will start for the Diamondbacks. His ERA is 5.33, and he has a record of 12 wins and 8 losses. The team’s ERA is 4.46, ranking 23rd, which shows room for improvement in pitching.

Red Sox Ready to Swing

The Boston Red Sox have some top hitters this season. Trevor Story leads with 23 home runs and 88 RBIs. Nathaniel Lowe has hit 18 home runs, ranking second on the team. Alex Bregman has a .284 batting average, showing his skills at the plate. The team’s batting average is .254, ranking 4th in the league. Their on-base percentage is .324, placing them 7th. They have hit 169 home runs, putting them 12th overall. Lucas Giolito will start on the mound for the Red Sox. His ERA is 3.38 with a record of 10 wins and 2 losses. The team’s ERA is 3.78, ranking 5th, showing solid pitching strength.

Final Betting Pick

The Arizona Diamondbacks are a good pick for the money line at -102. They have a home record of 37-33, showing they play well at Chase Field. Brandon Pfaadt’s win-loss record of 12-8, despite a higher ERA, indicates he knows how to secure wins. Their recent three-game win streak adds to their momentum.

The over 9.0 runs at -105 is also a solid choice. The Diamondbacks scored 10 runs in their last game against the Red Sox, showing they can hit well. The Red Sox have a strong offense too, with players like Trevor Story and Nathaniel Lowe capable of producing runs. This makes a high-scoring game likely.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.