The St. Louis Cardinals will play against the San Francisco Giants on Wednesday, September 24, 2025. The game will take place at Oracle Park in San Francisco, CA, starting at 9:45 PM. The Cardinals come in with a record of 78-80, while the Giants hold a record of 77-81. The weather forecast for the game is overcast clouds with a light breeze. Fans can watch the game on FDSMW.

Cardinals vs. Giants Betting Prediction

• Money Line Prediction: St. Louis Cardinals +106. The Cardinals have won their last three games and are playing well, while the Giants have struggled with a 2-8 record in their last ten games. The Cardinals’ recent form makes them a better value bet.
• Over/Under Prediction: Over 7.5 (-110). Both teams have been involved in high-scoring games recently, with the Cardinals scoring nine and six runs in their last two games against the Giants. The Giants have also shown they can score, making the over a favorable choice.

Team Trends

• The St. Louis Cardinals have a road record of 34-43 this season.
• The San Francisco Giants have a home record of 38-39 this season.
• The Cardinals are currently on a three-game winning streak.
• The Giants have lost their last two games and are 2-8 in their last ten games.
• The Cardinals defeated the Giants 9-8 on September 23, 2025, with 15 hits and 2 home runs.

Cardinals vs Giants Preview

The St. Louis Cardinals are set to take on the San Francisco Giants at Oracle Park. The Cardinals have a record of 78-80 and are looking to extend their three-game winning streak. They have been strong in their last ten games, winning six. Sonny Gray will start on the mound for the Cardinals. He has a 14-8 record with a 4.33 ERA and a 1.23 WHIP.

The Giants, with a 77-81 record, aim to break their two-game losing streak. They have struggled recently, winning only two of their last ten games. JT Brubaker will start for the Giants. He has a 3.65 ERA and a 1.22 WHIP, but this will be his first decision of the season. Fans can catch the game on FDSMW at 9:45 PM.

Giants Ready to Swing Big

The San Francisco Giants have some powerful hitters this season. Rafael Devers leads with 33 home runs and 106 RBIs. He ranks first on the team in both categories. Willy Adames and Matt Chapman also provide strength at the plate. Adames has hit 28 home runs, while Chapman has added 21. Both are key players for the Giants’ offense. JT Brubaker will start on the mound for the Giants. He has an ERA of 3.65 and a WHIP of 1.22. The Giants’ pitching ranks 12th in earned run average this season.

Cardinals Seek to Outshine Giants

The St. Louis Cardinals have some strong hitters in their lineup. Willson Contreras leads the team with 20 home runs and 80 RBIs. Alec Burleson and Iván Herrera also contribute with 18 and 19 home runs, respectively. Alec Burleson has a batting average of .294, the highest on the team. Iván Herrera follows with a .283 average. Brendan Donovan adds depth with a .287 average and 63 runs. Sonny Gray will be the starting pitcher for the Cardinals. He has an ERA of 4.33 and a WHIP of 1.23. The Cardinals’ pitching ranks 20th in earned run average this season.

Final Betting Pick

The Cardinals are a good pick for the money line at +106. They have won their last three games, including two against the Giants. Their recent form on the road shows they can perform well away from home. The Giants have struggled, with a 2-8 record in their last ten games, making the Cardinals a better value bet.

The over 7.5 runs is a solid choice given both teams’ recent scoring trends. The Cardinals scored nine and six runs in their last two games against the Giants. The Giants have also shown they can score, as seen in their recent games. With both teams having capable offenses, the over looks favorable.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.