Chicago Cubs vs Cincinnati Reds MLB Betting Prediction

MLB Chicago Cubs vs Cincinnati Reds Prediction 9/18

The Chicago Cubs will visit the Cincinnati Reds on Thursday, September 18, 2025, at 7:15 PM. The game will take place at the Great American Ball Park in Cincinnati, OH. Fans can catch the action on FOX, and the weather is expected to be warm with clear skies. The Cubs hold a record of 88-64, while the Reds sit at 76-76.

Cubs vs. Reds Betting Prediction

  • Money Line Prediction: Chicago Cubs +104. The Cubs have been strong on the road with a 42-35 record and are on a four-game winning streak. The Reds have a balanced home record but have been inconsistent in their last ten games.
  • Over/Under Prediction: Under 9.0 (-105). Hunter Greene’s solid ERA of 3.01 and Colin Rea’s recent performance suggest a lower-scoring game, especially with both teams having decent pitching stats this season.

Team Trends

  • The Chicago Cubs have a record of 88-64 and are on a 4-game winning streak.
  • The Cincinnati Reds hold a 76-76 record and have a home record of 40-34.
  • The Cubs recently won against the Pittsburgh Pirates with a score of 8-4, collecting 10 hits and 2 home runs.
  • The Reds recently defeated the St. Louis Cardinals 6-2, with Spencer Steer driving in 5 runs.
  • The game will be played at the Great American Ball Park in Cincinnati, with clear skies expected.

Cubs vs Reds Preview

The Chicago Cubs are heading to Cincinnati with a strong record of 88-64. They are currently ranked second in their division. The Cubs have been performing well recently, with a four-game winning streak and a 7-3 record in their last ten games. Colin Rea will take the mound for the Cubs. He has a 4.23 ERA and a 1.31 WHIP, with a 10-6 win-loss record this season.

The Cincinnati Reds, on the other hand, have an even 76-76 record and are third in the division. They have won one game in a row and are 5-5 in their last ten games. Hunter Greene will start as the pitcher for the Reds. Greene has a 3.01 ERA and a 0.99 WHIP, along with a 6-4 win-loss record. The game will be played at the Great American Ball Park, and the weather is expected to be warm with clear skies. Fans can watch the game on FOX.

Cincinnati Reds: Key Players and Pitching Strength

The Cincinnati Reds have some strong hitters this season. Elly De La Cruz leads the team with 19 home runs and 99 runs. Spencer Steer and Matt McLain add power with 18 and 14 home runs, respectively. On the pitching side, Hunter Greene stands out for the Reds. His ERA is 3.01, and he has a WHIP of 0.99. Greene’s record shows 6 wins and 4 losses this season. The Reds’ team batting average is .246, ranking 10th in the league. Their on-base percentage is .316, while their slugging percentage is .391. With 153 home runs, the Reds rank 18th in this category.

Chicago Cubs: Strong Bats and Solid Pitching

The Chicago Cubs have a lineup that can hit. Michael Busch leads the team with 29 home runs. Seiya Suzuki follows with 27 home runs and 91 RBIs. Nico Hoerner has the best batting average on the team at .303. The Cubs’ team batting average is .250, placing them 8th in the league. Their on-base percentage is .321, also ranked 8th. The team has hit 205 home runs, ranking 5th in this category. Colin Rea will start for the Cubs. His ERA stands at 4.23, and his WHIP is 1.31. Rea has a record of 10 wins and 6 losses this season.

Final Betting Pick

The Chicago Cubs have been performing well on the road, with a 42-35 record. They are also on a four-game winning streak, showing strong momentum. This makes the Cubs a solid pick for the money line at +104.

For the over/under, the prediction is under 9.0. Hunter Greene’s ERA of 3.01 indicates he can limit runs. Colin Rea’s recent performance also supports a lower-scoring game. Both teams have decent pitching stats, which suggests fewer runs will be scored.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.