The Chicago Cubs take on the Cincinnati Reds at Great American Ball Park on Friday, September 19, 2025, at 6:40 PM. The Cubs, with a record of 88-65, look to bounce back from a recent loss. The Reds, at 77-76, aim to extend their winning streak. The game will air on MARQ, and the weather is expected to be very hot with scattered clouds.

Cubs vs. Reds Betting Prediction

• Money Line Prediction: Chicago Cubs -125. The Cubs have a better overall record and have been strong in their last ten games with a 7-3 record. They also have a solid road record this season.
• Over/Under Prediction: Under 8.5 (-110). Both starting pitchers have low ERAs, and the previous game between these teams ended with a low score of 1-0.

Team Trends

• The Chicago Cubs have a road record of 42-36 this season.
• The Cincinnati Reds have a home record of 41-34 this season.
• The Cubs lost their last game against the Reds with a score of 1-0.
• The Reds are currently on a 2-game winning streak.
• The game will be played at Great American Ball Park in Cincinnati, OH.

Cubs vs Reds Preview

The Chicago Cubs are set to meet the Cincinnati Reds at Great American Ball Park. With a record of 88-65, the Cubs aim to recover from their recent loss. Their starting pitcher, Shota Imanaga, holds an ERA of 3.29 and a WHIP of 0.95. He will look to guide the Cubs back to winning form.

The Reds, with a record of 77-76, have won their last two games. They hope to continue their winning streak. Nick Lodolo will take the mound for the Reds, boasting an ERA of 3.30 and a WHIP of 1.04. The game will be played under very hot conditions with scattered clouds, and it will air on MARQ.

Reds Ready to Hit the Diamond

The Cincinnati Reds have some strong hitters in their lineup. Elly De La Cruz leads the team with a batting average of .261. He has played 153 games and hit 19 home runs. Spencer Steer is another key player for the Reds. He has a batting average of .240 and has hit 18 home runs in 137 games. Matt McLain has also contributed with 14 home runs and a batting average of .222. The Reds’ team batting average stands at .245, ranking 11th in the league. Their on-base percentage is .315, placing them 12th. With 153 home runs, they are ranked 17th in the league.

Cubs Look to Shine on the Road

The Chicago Cubs have a strong lineup this season. Seiya Suzuki stands out with 27 home runs and a batting average of .244. He is second on the team in home runs and leads in RBIs with 91. Dansby Swanson and Michael Busch are key players for the Cubs. Swanson has a batting average of .249 and has hit 22 home runs. Busch leads the team with 29 home runs and a batting average of .257. Nico Hoerner brings consistency to the lineup with a .301 batting average. The Cubs’ team batting average is .249, which ranks 9th in the league. Their on-base percentage is .320, placing them 8th.

Final Betting Pick

The Cubs’ money line at -125 is a solid pick. They have a strong road record of 42-36 and have been on a roll with a 7-3 record in their last ten games. The Cubs’ recent performances against the Pirates, where they secured multiple wins, highlight their ability to perform well away from home.

The under 8.5 prediction is supported by the starting pitchers’ low ERAs. Shota Imanaga and Nick Lodolo both have ERAs around 3.30, indicating they can keep the scoring low. The previous game between these teams ended 1-0, showing that both teams can limit runs effectively.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.