The Cincinnati Reds will play against the San Diego Padres on Wednesday, September 10, 2025, at 8:40 PM. The game will take place at PETCO Park in San Diego, CA. Fans can catch the action on FDSOH, with weather conditions expected to be warm and breezy, accompanied by scattered clouds.

Reds vs. Padres Betting Prediction

• Money Line Prediction: Padres -163. The Padres have a strong home record of 44-26. This gives them an edge playing at PETCO Park.
• Over/Under Prediction: Under 7.5 (-112). Both starting pitchers have ERAs under 3.00, suggesting a low-scoring game.

Team Trends

• The Cincinnati Reds have a road record of 33-38 this season.
• The San Diego Padres hold a strong home record of 44-26.
• In their last game, the Reds beat the Padres 4-2.
• The Padres have a division record of 26-19 in the NL West.
• The Reds are ranked 3rd in the NL Central, trailing by 15 games.

Reds vs Padres Preview

The Cincinnati Reds will take on the San Diego Padres in what should be an exciting game at PETCO Park. The Reds have a record of 73-72 and are currently third in their division. They are coming off a win and have been even in their last ten games, going 5-5.

On the mound for the Reds will be Andrew Abbott, who has a solid ERA of 2.88 and a WHIP of 1.15. He will face Nick Pivetta from the Padres, who has an ERA of 2.85 and a WHIP of 0.96. The Padres hold a record of 79-66 and are second in their division. They are looking to bounce back from a loss and have gone 4-6 in their last ten games.

San Diego Padres: Key Players and Stats

The San Diego Padres have a strong lineup with Manny Machado leading the way. He has played 145 games with a batting average of .276. Machado ranks first on the team in home runs, runs, and RBIs. Xander Bogaerts is another key player for the Padres. He has a batting average of .262 over 131 games. Bogaerts ranks third on the team in home runs and runs. Ryan O’Hearn has contributed significantly to the Padres’ offense. He has a batting average of .276 in 128 games. O’Hearn ranks second on the team in home runs and runs.

Cincinnati Reds: Key Hitters and Pitching Insights

Elly De La Cruz stands out for the Reds. He has a batting average of .267 over 145 games. De La Cruz leads the team in home runs with 19, runs with 96, and RBIs with 81. Spencer Steer is another important player for the Reds. He has played 133 games and has a batting average of .237. Steer ranks second on the team with 17 home runs and 64 RBIs. Andrew Abbott is the starting pitcher for the Reds. He has an ERA of 2.88 and a WHIP of 1.15. Abbott’s record is 8 wins and 6 losses this season.

Final Betting Pick

The Padres have a strong home record of 44-26, which makes them a good pick for the money line at -163. Playing at PETCO Park has been favorable for them this season. Nick Pivetta, their starting pitcher, has an ERA of 2.85, which is one of the reasons they have been successful at home.

The over/under is set at 7.5, and going under seems likely with both starting pitchers having ERAs under 3.00. Andrew Abbott for the Reds has an ERA of 2.88, which suggests he can keep the game low-scoring. The Padres’ pitching staff ranks third in ERA this season, which further supports the under bet.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.