Cincinnati Reds vs San Diego Padres MLB Betting Prediction

MLB Cincinnati Reds vs San Diego Padres Prediction 9/8

The Cincinnati Reds will play against the San Diego Padres on Monday, September 8, 2025. The game will take place at PETCO Park in San Diego, CA, starting at 9:40 PM. Fans can expect clear skies with a light breeze during this night game, which will be broadcast on SDPA. The Reds have a record of 72-71, while the Padres hold a 78-65 record this season.

Reds vs. Padres Betting Prediction

  • Money Line Prediction: Cincinnati Reds +119. The Reds have a solid starting pitcher in Nick Lodolo, who has a better ERA and WHIP than Yu Darvish of the Padres. Despite the Reds’ road struggles, Lodolo’s performance gives them a chance to win.
  • Over/Under Prediction: Over 7.5 (-113). Both teams have shown they can score runs, and with Darvish’s high ERA, there could be plenty of scoring opportunities. The Padres’ recent games have also been high-scoring.

Team Trends

  • The Cincinnati Reds have a road record of 32-37 this season.
  • The San Diego Padres hold a strong home record of 43-25.
  • The Reds have won their last two games against the New York Mets.
  • The Padres are also on a two-game winning streak, having defeated the Colorado Rockies in their last two games.
  • The game will take place at PETCO Park, an outdoor field in San Diego.

Reds vs Padres Preview

The Cincinnati Reds are set to challenge the San Diego Padres at PETCO Park. Both teams are coming off two-game winning streaks. The Reds have a record of 72-71, while the Padres stand at 78-65. The game starts at 9:40 PM, and the weather is expected to be clear with a light breeze.

Nick Lodolo will take the mound for the Reds. He has an ERA of 3.22 and a WHIP of 1.04. Yu Darvish will start for the Padres. His ERA is 5.75 with a WHIP of 1.18. Fans can watch the game on SDPA.

Padres’ Performance and Key Players

The San Diego Padres have shown solid performance in hitting this season. Manny Machado leads the team with a batting average of .280 and 23 home runs. Xander Bogaerts and Luis Arraez also contribute with batting averages of .262 and .285, respectively. In the pitching department, Yu Darvish is set to start for the Padres. His current ERA is 5.75 with a WHIP of 1.18. Despite his win-loss record of 3-5, he aims to improve in the upcoming game. Team stats reflect a batting average of .253, ranking them 6th. Their on-base percentage is .320, placing them 8th. The Padres’ pitching has an ERA of 3.68, which ranks 4th, and they lead the league with a batting average against of .226.

Reds’ Road Performance and Key Contributors

The Cincinnati Reds have a batting average of .248 this season, placing them 11th in the league. Elly De La Cruz is a standout player with a .267 average and 19 home runs. Spencer Steer adds value with 17 home runs and a .239 average. On the pitching side, Nick Lodolo will start for the Reds. He has an ERA of 3.22 and a WHIP of 1.04. His win-loss record stands at 8-7, showing he has been effective on the mound. The Reds’ team ERA is 3.94, ranking them 15th in the league. Their batting average against is .237, which ranks 6th. With 63 quality starts, they are 4th in the league.

Final Betting Pick

The Reds have a chance to win with Nick Lodolo on the mound. His ERA and WHIP are better than Yu Darvish’s. Lodolo’s pitching can help the Reds overcome their road record of 32-37.

The over 7.5 total runs is a good pick for this game. Both teams have shown they can score runs. The Padres have had high-scoring games recently, and Darvish’s high ERA might lead to more runs.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.