The Cleveland Guardians will play against the Detroit Tigers on Tuesday, September 16, 2025. The game is at Comerica Park in Detroit, MI, starting at 6:40 PM. The Guardians have a record of 78-71 and are on a 4-game winning streak, while the Tigers hold an 85-65 record and are ranked first in the AL Central. Weather is expected to be warm with a light breeze and a few clouds. Tune in to CLEG to catch the action.

Guardians vs. Tigers Betting Prediction

• Money Line Prediction: Cleveland Guardians +123. The Guardians have won 9 of their last 10 games and are on a 4-game win streak. Their recent form makes them a good value pick against the Tigers.
• Over/Under Prediction: Under 8.0 (-105). Both starting pitchers have solid ERAs, and the Tigers have struggled offensively in recent games, making the under a reasonable choice.

Team Trends

• The Cleveland Guardians have a current streak of winning four games in a row.
• The Detroit Tigers hold the top spot in the AL Central Division with a record of 85-65.
• Cleveland has been strong on the road with a balanced record of 37-37 this season.
• The Detroit Tigers have a solid home record of 46-29 at Comerica Park.
• The Cleveland Guardians have won nine of their last ten games.

Guardians vs Tigers Preview

The Cleveland Guardians are set to take on the Detroit Tigers at Comerica Park. Cleveland is on a strong run, winning their last four games. Joey Cantillo will be on the mound for the Guardians. He has an ERA of 3.36 and a record of 5-3 this season. Cantillo will aim to keep the Guardians’ momentum going.

The Detroit Tigers lead the AL Central and have a record of 85-65. Casey Mize will pitch for the Tigers. Mize has a 14-5 record with an ERA of 3.83. The Tigers are looking to strengthen their top spot in the division. This game will be an important one for both teams as they push towards the end of the season.

Detroit Tigers: Batting and Pitching Insights

The Detroit Tigers have some key players leading their offense. Spencer Torkelson stands out with 28 home runs, ranking 14th in the league. Gleyber Torres and Zach McKinstry also contribute with consistent performances. In the pitching department, Casey Mize is set to start for the Tigers. He has a 3.83 ERA and a 14-5 win-loss record. His WHIP of 1.27 shows his ability to control games. As a team, the Tigers hold a .249 batting average, placing them 9th in the league. Their on-base percentage is .318, and they have hit 187 home runs this season. These stats reflect their solid offensive efforts this year.

Cleveland Guardians: Key Players and Pitching Strength

The Cleveland Guardians have some strong hitters leading their lineup. José Ramírez shines with a .281 batting average and 28 home runs. He also leads the team with 92 runs and 77 RBIs. Kyle Manzardo adds power with 26 home runs. Gabriel Arias and Daniel Schneemann also contribute with their bats. The team has hit 154 home runs this season, ranking 20th in the league. On the mound, Joey Cantillo will start for the Guardians. He has a 3.36 ERA and a 5-3 win-loss record. His WHIP of 1.31 shows he can handle pressure on the mound.

Final Betting Pick

The Cleveland Guardians are on a strong run, winning 9 of their last 10 games. Their recent success includes a 4-game win streak, making them a solid pick at +123 against the Tigers. Away from home, the Guardians have a balanced record of 37-37, showing they can compete on the road.

Both teams have starting pitchers with solid ERAs, suggesting a low-scoring game. Joey Cantillo of the Guardians has an ERA of 3.36, while Casey Mize of the Tigers has an ERA of 3.83. The Tigers have struggled offensively, with a batting average of .225, ranked 22nd. This supports the choice of betting on the total score being under 8.0 runs.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.