The Cleveland Guardians will take on the Detroit Tigers on Wednesday, September 17, 2025, at 6:40 PM. The game will be held at Comerica Park in Detroit, MI. Fans can expect a warm evening with clear skies and calm winds. The game will be broadcast on FDSDE.

Guardians vs. Tigers Betting Prediction

• Money Line Prediction: Cleveland Guardians +127. The Guardians are on a 5-game win streak and have been strong on the road. Their recent form gives them an edge against the Tigers, who have lost 6 of their last 10 games.
• Over/Under Prediction: Over 8.0 (-112). Both teams have shown they can score, as seen in their recent game with a total of 12 runs. With the Tigers’ pitching struggles, expect another high-scoring game.

Team Trends

• The Cleveland Guardians have a recent strong performance with a 5-game win streak and a 9-1 record in their last 10 games.
• Detroit Tigers hold the first position in the AL Central with an overall record of 85-66.
• The Guardians recently defeated the Tigers 7-5 in their last game, with Joey Cantillo pitching 5 innings.
• Detroit Tigers have a solid home record this season, winning 46 out of 76 games at Comerica Park.
• The game will be played at Comerica Park in Detroit, MI, with clear skies and a calm wind expected.

Guardians vs Tigers Preview

The Cleveland Guardians are on a hot streak, winning their last five games. They have a strong record of 79-71 and are second in their division. Gavin Williams will start for the Guardians. He has a solid ERA of 3.16 and a record of 10-5. The Guardians are looking to keep their momentum going against the Tigers.

The Detroit Tigers are currently leading their division with an 85-66 record. However, they have been inconsistent lately, with a 4-6 record in their last ten games. Jack Flaherty will take the mound for the Tigers. His ERA is 4.69, and he has a record of 8-13. The Tigers hope to bounce back at home with a win at Comerica Park.

Detroit Tigers: Key Players and Performance

The Detroit Tigers have some strong hitters this season. Spencer Torkelson leads the team with 29 home runs. He also ranks first on the team in runs and RBIs. Gleyber Torres has been another important player. He has a batting average of .254 and 16 home runs. Torres ranks second on the team in runs and RBIs. Zach McKinstry and Colt Keith have also contributed. McKinstry has a batting average of .261, while Keith has hit 13 home runs. Both players have helped the Tigers in different ways.

Guardians Gear Up for Game

The Cleveland Guardians have some standout players this season. José Ramírez is a key figure, playing in 146 games. He leads the team with 28 home runs, 94 runs, and 78 RBIs. His batting average is .282. Kyle Manzardo is another important player for the Guardians. He has played in 130 games and hit 26 home runs. His batting average is .241, and he ranks second in runs and RBIs for the team. Gabriel Arias, Daniel Schneemann, and Bo Naylor also contribute to the team. Arias has 11 home runs, while Schneemann has the same number. Naylor has hit 12 home runs in 114 games.

Final Betting Pick

The Cleveland Guardians have been strong on the road, with a 38-37 record away from home. Their recent 5-game win streak adds to their momentum. Gavin Williams, their starting pitcher, has a solid 3.16 ERA, which can help them against the Tigers’ lineup.

The over/under prediction of over 8.0 is backed by both teams’ recent performances. In their last game, they combined for 12 runs, and the Tigers’ pitching has struggled. With Jack Flaherty’s 4.69 ERA, the Guardians could find success at the plate, leading to a high-scoring game.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.