On Saturday, September 20, 2025, the Cleveland Guardians will take on the Minnesota Twins at Target Field in Minneapolis, MN. The game is set for 2:10 PM and will air on CLEG. The Guardians have an 82-71 record and are on an 8-game winning streak, while the Twins hold a 66-87 record and have lost their last three games. Weather forecasts predict a mild day with scattered clouds and a calm crosswind.

Guardians vs. Twins Betting Prediction

• Money Line Prediction: Cleveland Guardians +108. The Guardians are on an 8-game winning streak and have a strong 9-1 record in their last 10 games. The Twins have lost their last 3 games and have a weaker home record.
• Over/Under Prediction: Under 7.5 (-110). Both teams have shown limited scoring in recent games, and with Joe Ryan’s solid ERA, runs might be hard to come by.

Team Trends

• The Cleveland Guardians are on an 8-game winning streak and have won 9 of their last 10 games.
• The Minnesota Twins have lost their last 3 games and have only won 3 of their last 10 games.
• Cleveland Guardians have a strong division record of 32-14 this season.
• The Twins have struggled at home with a record of 37-41 this season.
• The Guardians recently defeated the Twins 6-2 in their last game at Target Field.

Guardians vs Twins Preview

The Cleveland Guardians are set to play against the Minnesota Twins at Target Field. The Guardians have been on a roll, winning their last eight games. They are second in their division and have a strong 82-71 record. The Twins, on the other hand, are fourth in their division with a 66-87 record and have lost their last three games. The weather looks mild with scattered clouds, making it a pleasant day for baseball.

Slade Cecconi will start on the mound for the Guardians. He has a 4.39 ERA and a 1.22 WHIP. Joe Ryan will pitch for the Twins, boasting a 3.35 ERA and a 1.02 WHIP. This game could be a test for the Twins as they try to end their losing streak. Fans can catch all the action on CLEG at 2:10 PM.

Twins Aim for Victory at Home

The Minnesota Twins have a strong lineup this season. Brooks Lee stands out with 15 home runs, ranking second on the team. His 62 RBIs are the most on the team, showing his ability to drive in runs. Ryan Jeffers has been reliable behind the plate. He has a batting average of .262 and has played in 114 games. His on-base percentage of .353 is a team highlight. Joe Ryan leads the Twins’ pitching staff. With a 13-8 record, he has a solid ERA of 3.35. His WHIP of 1.02 shows his control on the mound.

Guardians Ready to Challenge on the Road

José Ramírez leads the Cleveland Guardians with power and consistency. He has hit 29 home runs and scored 98 runs. His batting average of .282 is also a key part of the team’s offense. Kyle Manzardo is another important player for the Guardians. He has played in 133 games and hit 26 home runs. His batting average is .238, but he contributes with 67 RBIs. Pitching for the Guardians is Slade Cecconi. His record is 6-6, with an ERA of 4.39. His WHIP of 1.22 shows he can manage base runners effectively.

Final Betting Pick

The Cleveland Guardians have been on a roll with an 8-game winning streak. Their recent performance on the road has been strong, with a 41-37 record. This makes the money line pick of Cleveland Guardians +108 appealing, as they have also won 9 of their last 10 games. The Minnesota Twins, on the other hand, have struggled at home with a 37-41 record and have lost their last 3 games. This contrast in form supports the pick for the Guardians to win.

For the over/under prediction, the choice of under 7.5 (-110) is based on recent scoring trends. Both teams have shown limited scoring in their recent games. Joe Ryan’s solid ERA of 3.35 suggests that runs might be limited in this game. The Guardians’ pitching has been effective, as seen in their recent 6-2 win over the Twins. These factors make the under 7.5 a sensible pick for this game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.