Colorado Rockies vs San Francisco Giants MLB Betting Prediction
PublishedSeptember 26, 2025,            Posted By: Maria Uebelhor
Last updated:September 26, 2025 ,

MLB Colorado Rockies vs San Francisco Giants Prediction 9/26

The Colorado Rockies will play against the San Francisco Giants on Friday, September 26, 2025, at 10:15 PM. The game will take place at Oracle Park in San Francisco, CA. Fans can watch the game on NBCS, and the weather is expected to be warm with a clear sky.

Rockies vs. Giants Betting Prediction

  • Money Line Prediction: San Francisco Giants -236. The Giants have a better record and are playing at home where they have a balanced 39-39 record. The Rockies have struggled on the road with an 18-60 record.
  • Over/Under Prediction: Under 8.0 (-107). The Giants have a mid-range ERA of 3.90, and the Rockies have struggled offensively, making a low-scoring game likely.

Team Trends

  • The Colorado Rockies have a road record of 18-60 this season.
  • The San Francisco Giants hold a home record of 39-39 this season.
  • In their last 10 games, the Rockies have a record of 2-8.
  • The Giants recently won against the St. Louis Cardinals with a score of 4-3.
  • The Rockies’ last game ended in a 6-2 loss against the Seattle Mariners.

Rockies vs Giants Preview

The Colorado Rockies are set to play against the San Francisco Giants at Oracle Park. The Rockies have struggled this season, holding a record of 43-116 and sitting at the bottom of their division. They have lost their last three games and have only won two of their last ten. Germán Márquez will start for the Rockies, bringing an ERA of 6.49 and a record of 3-15.

The Giants have a record of 78-81 and rank fourth in their division. They recently snapped a losing streak with a win and have gone 3-7 in their last ten games. Trevor McDonald will take the mound for the Giants. This will be his first game of the season, and he enters with an ERA of 3.38. The game will be held under clear skies, making for a pleasant night of baseball.

San Francisco Giants: Key Players and Stats

Rafael Devers leads the Giants with 34 home runs and 107 RBIs. He ranks 11th in the league for home runs and 7th for RBIs. Devers has played 160 games, maintaining a batting average of .251. Willy Adames is another strong hitter for the Giants. He has 28 home runs and 84 RBIs in 157 games. Adames holds a batting average of .225 and ranks 16th in the league for home runs. The Giants’ team batting average is .235, ranking 16th in the league. They have hit 168 home runs, placing them 17th in that category. The team has also accumulated 543 walks, ranking 7th in the league.

Rockies’ Road Challenge: Key Players and Stats

Hunter Goodman stands out for the Rockies. He has hit 30 home runs and has 90 RBIs. His batting average is .278, and he leads the team in home runs and RBIs. Ezequiel Tovar has played 93 games this season. He has a batting average of .254 with 8 home runs. Tovar also has 30 RBIs and 43 runs. The Rockies have a team batting average of .238. Their on-base percentage is .293, which ranks 24th in the league. They have hit 156 home runs, ranking 20th.

Final Betting Pick

The Giants are favored on the money line at -236. This is due to their stronger overall record and balanced performance at home. Playing at Oracle Park, they have a 39-39 record. This contrasts with the Rockies’ struggles on the road, where they have an 18-60 record. The Giants’ home advantage and the Rockies’ poor away performance make this a solid pick.

The under 8.0 is a good choice given the Giants’ mid-range ERA of 3.90. Their pitching has been effective, limiting opponents’ scoring opportunities. Meanwhile, the Rockies have struggled offensively, as shown by their recent games. With Germán Márquez’s high ERA of 6.49, the Rockies might not score much, supporting a low-scoring game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.