Detroit Tigers vs Boston Red Sox MLB Betting Prediction

MLB Detroit Tigers vs Boston Red Sox Prediction 9/26

The Detroit Tigers will take on the Boston Red Sox at Fenway Park on Friday, September 26, 2025, at 7:10 PM. The Tigers have a record of 86-73 and are ranked second in their division. Meanwhile, the Red Sox hold a record of 87-72 and sit third in their division. Fans can watch the game on APLTV, and the weather forecast predicts a warm day with a light breeze and broken clouds.

Tigers vs. Red Sox Betting Prediction

  • Money Line Prediction: Boston Red Sox -121. The Red Sox have a solid home record of 46-32 and have been playing well recently with a 6-4 record in their last 10 games. With Kyle Harrison’s strong pitching stats, they have an edge in this game.
  • Over/Under Prediction: Under 8.5 (-101). Both teams have strong pitching with Casey Mize and Kyle Harrison on the mound, and the Red Sox have a top 5 ERA this season. This suggests a low-scoring game.

Team Trends

  • The Detroit Tigers have a road record of 40-38 this season.
  • The Boston Red Sox have a home record of 46-32 this season.
  • In their last game, the Detroit Tigers won 4-2 against the Cleveland Guardians.
  • The Boston Red Sox lost their last game 6-1 against the Toronto Blue Jays.
  • Fenway Park, the venue for the game, is known for being an outdoor field.

Tigers vs Red Sox Preview

On Friday night, the Detroit Tigers travel to Fenway Park to play the Boston Red Sox. The Tigers, with a record of 86-73, are second in their division. They recently ended a losing streak, winning their last game. Their starting pitcher, Casey Mize, holds a 14-6 record with a 3.91 ERA. Fans hope he can deliver another strong performance.

The Red Sox, holding an 87-72 record, are third in their division. They look to bounce back after a recent loss. Kyle Harrison will take the mound for Boston. Harrison has a 3.58 ERA and a 1-1 record. Both teams aim to improve their standings as the season nears its end. The game will be broadcast on APLTV, and the weather is expected to be warm with broken clouds.

Red Sox Ready to Shine at Fenway

The Boston Red Sox are having a solid season with their bats. They rank 3rd in batting average at .254. Trevor Story leads the team with 25 home runs and 91 runs scored. Nathaniel Lowe and Alex Bregman are key players for the Red Sox. Lowe has hit 18 home runs in 150 games. Bregman, with a .273 batting average, has also contributed 18 home runs. On the mound, Kyle Harrison will start for the Red Sox. His ERA is 3.58, and he has a WHIP of 1.19. Harrison’s record stands at 1-1 this season.

Tigers Look to Roar in Boston

The Detroit Tigers have some strong hitters this season. Spencer Torkelson leads the team with 31 home runs and 82 runs scored. Gleyber Torres follows with a .258 batting average and 16 home runs. Zach McKinstry has been reliable with a .261 batting average. Colt Keith and Dillon Dingler each have 13 home runs. Trey Sweeney, though struggling with a .197 average, has contributed 6 home runs. On the mound, Casey Mize will start for the Tigers. Mize has an ERA of 3.91 and a WHIP of 1.28. His record this season is 14-6.

Final Betting Pick

The Boston Red Sox are a strong pick for the money line at -121. They have a solid home record of 46-32, showing they play well at Fenway Park. In their last ten games, they have a 6-4 record, which indicates they are in good form. Kyle Harrison’s pitching gives them an edge, as he has a 3.58 ERA and a 1.19 WHIP, making him a reliable starter for this game.

For the over/under prediction, choosing under 8.5 (-101) seems wise. Both teams have strong pitching with Casey Mize and Kyle Harrison on the mound. The Red Sox have a top 5 ERA this season at 3.74, suggesting they can limit the Tigers’ scoring. With both teams having solid pitching, a low-scoring game is likely.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.