The Detroit Tigers will take on the Cleveland Guardians on Tuesday, September 23, 2025, at Progressive Field in Cleveland, OH. The game starts at 6:40 PM and will be aired on CLEG. The weather forecast predicts a mild day with light rain and a gentle breeze.

Tigers vs. Guardians Betting Prediction

• Money Line Prediction: Cleveland Guardians +132. The Guardians are on a strong run, winning 9 of their last 10 games. At home, they have a good record, and their recent form makes them a solid choice.
• Over/Under Prediction: Under 6.5 (-107). Both teams have strong starting pitchers with low ERAs. The Tigers’ recent games have also been low-scoring, making the under a good bet.

Team Trends

• The Detroit Tigers have lost their last six games and have a 1-9 record in their last 10 games.
• The Cleveland Guardians have won nine of their last 10 games, with only one loss.
• The Tigers have a road record of 39-36 this season.
• The Guardians have a home record of 41-34 this season.
• Weather at Progressive Field is forecasted to be mild with a light breeze and light rain.

Tigers vs Guardians Preview

The Detroit Tigers are set to meet the Cleveland Guardians at Progressive Field. The Tigers, with an 85-71 record, hold the top spot in their division. However, they have hit a rough patch, losing their last six games. Their recent form shows just one win in their last ten games.

On the mound for the Tigers is Tarik Skubal. He has an ERA of 2.23 and a WHIP of 0.88. Skubal’s record stands at 13-5. The Guardians, with an 84-72 record, are second in the division. They have been strong lately, winning nine out of their last ten games. Gavin Williams will pitch for the Guardians, with an ERA of 3.06 and a WHIP of 1.28. Williams has an 11-5 record this season.

Guardians Gear Up for Home Game

The Cleveland Guardians have a key player in José Ramírez. He has played 152 games this season. His batting average is .282, and he leads the team with 30 home runs. Kyle Manzardo is another strong hitter for the Guardians. He has 26 home runs in 136 games. His batting average is .236, placing him second in home runs for the team. Gavin Williams will start as the pitcher for the Guardians. He has an ERA of 3.06 and a WHIP of 1.28. His record this season is 11 wins and 5 losses.

Detroit Tigers Prepare for Battle

Spencer Torkelson leads the Tigers in home runs. He has hit 31 homers in 150 games. His batting average is .243, and he has driven in 78 runs. Gleyber Torres is another key player for the Tigers. He has played 140 games this season. Torres has a batting average of .261 and has hit 16 home runs. On the mound, Tarik Skubal will pitch for the Tigers. He has a strong ERA of 2.23 and a WHIP of 0.88. Skubal’s record this season is 13 wins and 5 losses.

Final Betting Pick

The Cleveland Guardians are a strong pick for the money line at +132. They have won 9 of their last 10 games, showing they are in good form. At home, they have a solid record of 41-34, which adds to their advantage.

For the over/under, going under 6.5 is a smart choice. Both teams have strong starting pitchers. Tarik Skubal of the Tigers has an ERA of 2.23, while Gavin Williams of the Guardians has a 3.06 ERA. Recent games for the Tigers have been low-scoring, which supports this pick.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.