Detroit Tigers vs Cleveland Guardians MLB Betting Prediction
PublishedSeptember 30, 2025,            Posted By: Maria Uebelhor
Last updated:September 30, 2025 ,

MLB Detroit Tigers vs Cleveland Guardians Prediction 9/30

The Detroit Tigers will take on the Cleveland Guardians on Tuesday, September 30, 2025, at Progressive Field. The game is set to start at 1:08 PM and will be aired on ESPN. Fans can expect a cool day with clear skies and a light breeze. Both teams are starting the season with a clean slate, each holding a 0-0 record.

Tigers vs. Guardians Betting Prediction

  • Money Line Prediction: Cleveland Guardians +139. The Guardians have a strong home record and a better division record compared to the Tigers. This makes them a good value pick for this game.
  • Over/Under Prediction: Under 6.0 (-110). Both starting pitchers have low ERAs, suggesting a low-scoring game is likely.

Team Trends

  • The Cleveland Guardians finished the regular season with a record of 88-74, ranking first in the AL Central.
  • The Detroit Tigers had a road record of 41-40 during the regular season.
  • The Cleveland Guardians had a home record of 45-36 in the regular season.
  • Both teams are part of the AL Central division.
  • The game will be played at Progressive Field in Cleveland, OH, with clear skies and a light breeze expected.

Tigers vs Guardians Preview

The Detroit Tigers are set to play against the Cleveland Guardians at Progressive Field. Both teams are looking to start their season strong with a win. The Tigers will rely on Tarik Skubal, who had an impressive previous season with an ERA of 2.21. Skubal’s performance could be key in giving the Tigers an early advantage.

On the other side, the Cleveland Guardians will have Gavin Williams on the mound. Williams had a solid season last year with an ERA of 3.06. The Guardians aim to use their home-field advantage to secure a victory. Fans can tune in on ESPN to catch the action in what is expected to be a competitive game.

Cleveland Guardians: Key Players and Stats

The Cleveland Guardians have some strong hitters leading their lineup. José Ramírez stands out with a batting average of .283. He has hit 30 home runs, ranking first on the team. Kyle Manzardo is another key player for the Guardians. He has played in 142 games with a batting average of .234. Manzardo has hit 27 home runs this season. Gabriel Arias plays a crucial role at shortstop. He has a batting average of .220 and has hit 11 home runs. Arias has also contributed 44 runs for the team.

Detroit Tigers: A Look at Their Lineup

The Detroit Tigers have some standout players in their lineup. Spencer Torkelson leads the team with 31 home runs. He has a batting average of .240 and has played in 155 games. Torkelson also leads the team with 82 runs. Gleyber Torres is another key player for the Tigers. He has a batting average of .256 and has hit 16 home runs. Torres has played in 145 games and scored 79 runs this season. Zach McKinstry holds a batting average of .259. He has hit 12 home runs in 144 games. McKinstry has also driven in 49 runs for the Tigers this season.

Final Betting Pick

The Cleveland Guardians are a good pick on the money line at +139. They have a strong home record of 45-36, which gives them an edge at Progressive Field. Their division record of 36-16 is also better than the Tigers, showing their strength against AL Central teams.

The under 6.0 prediction is supported by the starting pitchers’ stats. Tarik Skubal of the Tigers has a low ERA of 2.21, and Gavin Williams of the Guardians has an ERA of 3.06. Both pitchers have shown they can limit runs, which points to a low-scoring game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.