Houston Astros vs Athletics MLB Betting Prediction

MLB Houston Astros vs Athletics Prediction 9/25

The Houston Astros will play against the Athletics on Thursday, September 25, 2025. The game will take place at Sutter Health Park in West Sacramento, CA. Fans can catch the action on SCHN at 3:35 PM under overcast skies.

Astros vs. Athletics Betting Prediction

  • Money Line Prediction: Athletics -101. The Athletics have been strong at home, winning their last two games against the Astros. Houston is on a losing streak, which makes the Athletics a good value bet.
  • Over/Under Prediction: Under 9.5 (-106). Both teams have struggled to score in recent games, and with Valdez and Ginn on the mound, runs may be limited.

Team Trends

  • The Houston Astros are currently on a 5-game losing streak and have a road record of 38-39.
  • The Athletics have won their last two games and have a home record of 35-42.
  • In their last game, the Athletics defeated the Astros 6-0 with Luis Severino pitching 6 1/3 scoreless innings.
  • The Astros have struggled in their last 10 games, going 4-6 during that span.
  • The game will take place at Sutter Health Park with overcast clouds and a light breeze expected.

Astros vs Athletics Preview

The Houston Astros are set to face the Athletics in an afternoon game at Sutter Health Park. The Astros, holding an 84-74 record, are in second place in their division. They are looking to break a five-game losing streak. Meanwhile, the Athletics, with a 75-83 record, are in fourth place and have won their last two games.

On the mound, the Astros will start Framber Valdez. He has a 3.75 ERA and a 12-11 record. The Athletics will counter with J.T. Ginn, who has a 4.57 ERA and a 4-6 record. Fans can watch the game on SCHN at 3:35 PM. The weather forecast calls for overcast skies with a light breeze.

Athletics Ready for Action

The Athletics have some strong hitters this season. Nick Kurtz leads the team with a batting average of .290. He also has 33 home runs and 81 RBIs, making him a key player to watch. Shea Langeliers is another important player for the Athletics. He has a batting average of .266 and has hit 31 home runs. His performance behind the plate is also vital for the team. Jacob Wilson has been consistent for the team. He has a batting average of .315 and has scored 62 runs. His presence in the lineup adds depth to the team’s hitting capabilities.

Astros Set for Competition

Jeremy Peña is a standout player for the Astros. He has a batting average of .304 and played in 125 games. His 17 home runs and 68 runs make him a key player for the team. Christian Walker is another strong hitter for the Astros. He leads the team with 23 home runs and has 82 RBIs. His batting average is .234, and he has played in 151 games. Yainer Diaz and Isaac Paredes add strength to the Astros lineup. Diaz has a batting average of .254 and hit 19 home runs. Paredes has hit 20 home runs and has a .254 batting average as well.

Final Betting Pick

The Athletics are a good pick on the money line at -101. They have won their last two games against the Astros at home. The Astros are struggling on the road with a 38-39 record, which adds to the Athletics’ advantage. The under 9.5 runs is another solid choice. Both teams have had trouble scoring lately. With Framber Valdez and J.T. Ginn pitching, the game may have limited runs. Valdez has a 3.75 ERA, and Ginn has a 4.57 ERA, which suggests a lower-scoring game.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.