The Houston Astros will take on the Los Angeles Angels at Angel Stadium of Anaheim on Friday, September 26, 2025, at 9:38 PM. The Astros have a record of 85-74 and are second in the AL West, while the Angels sit at 71-88 and are fifth in the division. Fans can expect a warm evening with a light breeze under broken clouds for this night game, which will be broadcast on SCHN.

Astros vs. Angels Betting Prediction

• Money Line Prediction: Houston Astros at -146. The Astros have a better record and are coming off a win. The Angels have struggled at home with a 38-40 record.
• Over/Under Prediction: Over 9.0 (-108). Both starting pitchers have ERAs near 5.00, and recent games for both teams have seen high scores.

Team Trends

• The Houston Astros have a balanced road record of 39-39 this season.
• The Los Angeles Angels have a home record of 38-40 this season.
• The Astros recently defeated the Athletics 11-5 with 12 hits and 5 extra base hits.
• The Angels lost their last game against the Royals 9-4, despite hitting 3 home runs.
• Jose Altuve of the Astros had a strong performance with 2 hits and 2 RBIs in their recent win over the Athletics.

Astros vs Angels Preview

The Houston Astros visit the Los Angeles Angels at Angel Stadium of Anaheim. The Astros have an 85-74 record and are second in the AL West. They aim to improve their recent 4-6 performance over the last ten games. Jason Alexander will start for the Astros. He has a 4.83 ERA and a 1.39 WHIP.

The Angels, with a 71-88 record, are fifth in the AL West. They have struggled recently, going 2-8 in their last ten games. Kyle Hendricks will take the mound for the Angels. Hendricks has a 4.79 ERA and a 1.28 WHIP. Fans can watch the game on SCHN and enjoy a warm evening with a light breeze under broken clouds.

Angels’ Home Game Preview

The Los Angeles Angels have some strong hitters this season. Zach Neto is leading the team with 26 home runs. He also has 82 runs and 62 RBIs, ranking first on the team in each category. Nolan Schanuel has been consistent at first base. He has a .267 batting average and 64 runs. His 12 home runs put him third on the team. The Angels’ starting pitcher for the game is Kyle Hendricks. Hendricks has an ERA of 4.79 and a record of 8-10. The team will look to him for a solid start.

Astros’ Road Game Outlook

The Houston Astros have a lineup with solid contributors. Christian Walker leads the team with 24 home runs and 85 RBIs. Jeremy Peña adds to the mix with a .304 batting average and 68 runs, placing him second in runs for the team. On the mound, the Astros will start Jason Alexander. He holds a 4.83 ERA and a 4-2 win-loss record. His WHIP is 1.39, and the team will depend on him to keep the Angels’ hitters in check. As a team, the Astros have a batting average of .250, ranking 7th in the league. Their on-base percentage stands at .315, placing them 12th. With 173 home runs, they rank 15th, showing their ability to hit for power.

Final Betting Pick

The Astros have a strong chance to win with their recent performance. They have an even road record of 39-39, showing they can compete away from home. Their recent 11-5 win against the Athletics highlights their ability to score runs.

The over 9.0 prediction is supported by both teams’ recent high-scoring games. The Astros scored 11 runs in their last game, while the Angels gave up 9 runs to the Royals. With both starting pitchers having ERAs near 5.00, expect more runs in this game.

All odds are courtesy of Action247 Sportsbook. Good luck!!

* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.