Milwaukee Brewers vs St. Louis Cardinals MLB Betting Prediction

MLB Milwaukee Brewers vs St. Louis Cardinals Prediction 9/21

The Milwaukee Brewers will take on the St. Louis Cardinals at Busch Stadium on Sunday, September 21, 2025, at 2:15 PM. The Brewers hold a strong record of 95-60, while the Cardinals stand at 75-80. Fans can expect an afternoon game with overcast clouds and a light breeze. The game will be broadcast on FDSMW.

Brewers vs. Cardinals Betting Prediction

  • Money Line Prediction: Milwaukee Brewers -137. The Brewers have a strong road record and are led by Freddy Peralta, who has a low ERA of 2.65. The Cardinals have struggled at home recently, which makes the Brewers a good choice.
  • Over/Under Prediction: Under 9.0 (-119). Both teams have shown solid pitching performances in recent games, and the weather conditions with a light breeze might keep the scoring low.

Team Trends

  • Milwaukee Brewers have an away record of 44-33 this season.
  • St. Louis Cardinals have a home record of 43-37 this season.
  • In the last game, Milwaukee Brewers won against the St. Louis Cardinals with a score of 3-2.
  • The Brewers have won six of their last ten games.
  • The Cardinals have lost seven of their last ten games.

Brewers vs Cardinals Preview

The Milwaukee Brewers are set to play the St. Louis Cardinals at Busch Stadium. The Brewers have a record of 95-60, leading their division. They have won 6 of their last 10 games. Freddy Peralta will start for the Brewers. He has a strong ERA of 2.65 and a record of 17-6.

The St. Louis Cardinals come into the game with a 75-80 record. They are fourth in their division and have struggled recently, winning only 3 of their last 10 games. Matthew Liberatore will pitch for the Cardinals. His ERA stands at 4.30, with a record of 7-12. Fans can watch the game on FDSMW.

St. Louis Cardinals: Key Players and Stats

The St. Louis Cardinals have some strong hitters this season. Willson Contreras leads the team with 20 home runs and 80 RBIs. Alec Burleson follows closely with 18 home runs and a .289 batting average. Brendan Donovan and Iván Herrera are also key players for the Cardinals. Donovan has a .282 batting average and 62 runs. Herrera adds to the team’s strength with 16 home runs and a .366 OBP. Matthew Liberatore will start as the pitcher for the Cardinals. He has a 4.30 ERA and a record of 7 wins and 12 losses. The Cardinals will need a solid performance from him against the Brewers.

Milwaukee Brewers: Key Players and Stats

Brice Turang is a standout for the Brewers. He leads the team with 18 home runs and 95 runs. His batting average is .286, and his on-base percentage is .356. William Contreras is another key player. He has 17 home runs and 89 runs. His batting average stands at .265, with an on-base percentage of .360. Freddy Peralta will start as the pitcher for the Brewers. He has an ERA of 2.65 and a record of 17 wins and 6 losses. His WHIP is 1.07, making him a strong presence on the mound.

Final Betting Pick

The Brewers are a solid pick for the money line. They have a strong road record at 44-33 and are led by Freddy Peralta, who has an ERA of 2.65. Peralta’s performance gives Milwaukee an edge, especially against the Cardinals’ starter, Matthew Liberatore, who has a higher ERA of 4.30.

Choosing the under 9.0 is a smart move. Both teams have shown good pitching in recent games. The Brewers have a team ERA of 3.61, which ranks them 2nd in the league. The Cardinals have struggled at home, and the weather conditions with a light breeze might keep the scoring low.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.