The New York Yankees will take on the Baltimore Orioles on Sunday, September 21, 2025, at Oriole Park at Camden Yards. The game is set for 1:35 PM and will be broadcast on YES. The weather forecast predicts overcast clouds with a mild breeze. The Yankees have a record of 87-68, while the Orioles stand at 73-82.

Yankees vs. Orioles Betting Prediction

• Money Line Prediction: Yankees -133. The Yankees have a better record and have won 7 of their last 10 games. They also won 6-1 against the Orioles recently.
• Over/Under Prediction: Under 8.5 (-114). Both teams have strong starting pitchers with low ERAs, suggesting a lower-scoring game.

Team Trends

• The New York Yankees have a strong road record of 43-37 this season.
• Baltimore Orioles have a home record of 37-40 this season.
• The Yankees recently won against the Orioles 6-1 on September 20th, 2025.
• The Orioles managed a win against the Yankees 4-2 on September 19th, 2025.
• The Yankees have been performing well lately with a 7-3 record in their last 10 games.

Yankees vs Orioles Preview

The New York Yankees and Baltimore Orioles are set to meet at Oriole Park at Camden Yards. The Yankees have an 87-68 record and are second in their division. They have won seven of their last ten games. The Orioles have a 73-82 record and are fifth in the division. They have split their last ten games evenly.

Cam Schlittler will start on the mound for the Yankees. He has a 3.41 ERA and a 1.35 WHIP. Kyle Bradish will pitch for the Orioles. He has a 2.45 ERA and a 1.09 WHIP. Both pitchers will aim to lead their teams to a win in this afternoon game. The weather is expected to be mild with overcast clouds.

Orioles’ Key Players and Stats

The Baltimore Orioles have some standout hitters this season. Gunnar Henderson leads the team with a .275 batting average. He has played 147 games and is second in home runs with 16. Jackson Holliday is another key player for the Orioles. He has a .247 batting average and leads the team with 17 home runs. Holliday has played in 144 games this season. Kyle Bradish is the starting pitcher for the Orioles in this game. He has an ERA of 2.45 and a WHIP of 1.09. Bradish has a win-loss record of 1-1 this season.

Yankees’ Top Performers and Game Strategy

The New York Yankees have strong hitters this season. Jazz Chisholm Jr. stands out with 30 home runs, leading the team. He has a .242 batting average and has played 123 games. Anthony Volpe has been active for the Yankees as well. He has played 146 games and hit 19 home runs. Volpe’s batting average is .210, and he ranks fourth on the team for home runs. Cam Schlittler is the starting pitcher for the Yankees in this game. He has an ERA of 3.41 and a WHIP of 1.35. Schlittler’s win-loss record is 3-3 this season.

Final Betting Pick

The Yankees are a solid pick for the money line at -133. They have a strong road record of 43-37 and have recently won 7 of their last 10 games. Their recent 6-1 win against the Orioles shows their ability to perform well away from home. With hitters like Jazz Chisholm Jr. and Aaron Judge leading the team, their offense is strong.

The under 8.5 is a good choice given the starting pitchers. Cam Schlittler for the Yankees has a 3.41 ERA, while Kyle Bradish for the Orioles has a 2.45 ERA. Both pitchers have shown they can limit runs, suggesting a lower-scoring game. The Orioles’ recent offensive struggles, scoring only 1 run in their last game against the Yankees, further support this prediction.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.