Pittsburgh Pirates vs Cincinnati Reds MLB Betting Prediction

MLB Pirates vs Cincinnati Reds Prediction 9/25

The Pittsburgh Pirates will take on the Cincinnati Reds on Thursday, September 25, 2025, at 12:40 PM. The game will be held at Great American Ball Park in Cincinnati, OH. The weather forecast predicts a mild day with light rain, and you can catch the game on SN PT.

Pirates vs. Reds Betting Prediction

  • Money Line Prediction: Pittsburgh Pirates +141. The Pirates have a four-game winning streak and have won the last two games against the Reds. Their recent form makes them a good value pick.
  • Over/Under Prediction: Under 8.0 (-106). Both teams have solid starting pitchers, and the previous games in the series have been low-scoring.

Team Trends

  • The Pittsburgh Pirates have a current winning streak of 4 games.
  • The Cincinnati Reds have a home record of 44-36 this season.
  • The Pirates recently won a game against the Reds with a score of 4-3.
  • The Reds have lost their last 2 games.
  • The game will be held at Great American Ball Park, with a weather forecast of light rain.

Pirates vs Reds Preview

The Pittsburgh Pirates are set to play against the Cincinnati Reds at Great American Ball Park. The Pirates come into this game with a record of 69-89 and are ranked fifth in their division. They are on a four-game winning streak, but their last 10 games show a balanced 5-5 record. Braxton Ashcraft will start on the mound for the Pirates. He has an ERA of 2.62 and a WHIP of 1.19, with a win-loss record of 4-3 this season.

On the other side, the Cincinnati Reds hold a record of 80-78 and are third in their division. They have lost their last two games but have a 6-4 record in their last 10 games. Nick Lodolo will be the starting pitcher for the Reds. Lodolo has an ERA of 3.44 and a WHIP of 1.08, with an 8-8 win-loss record. The game is set for Thursday, September 25, 2025, at 12:40 PM. The weather forecast predicts a mild day with light rain, so fans should prepare accordingly.

Cincinnati Reds: Key Players and Stats

Elly De La Cruz is a standout player for the Reds. He has played 158 games with a batting average of .266. He leads the team in home runs with 21, runs with 101, and RBIs with 85. Spencer Steer has also been important for the team. He has played 142 games with a batting average of .240. Steer is tied with De La Cruz for the most home runs on the team, also hitting 21. Nick Lodolo will be the starting pitcher for the Reds. His ERA is 3.44, and his WHIP is 1.08. Lodolo has an even record of 8 wins and 8 losses this season.

Pirates Seek to Make Waves Against Reds

Andrew McCutchen leads the Pirates with his hitting skills. He has played 132 games and holds a batting average of .240. McCutchen also leads the team in home runs with 13 and has scored 50 runs. Spencer Horwitz is another important player for the Pirates. He has played 104 games with a batting average of .262. Horwitz has hit 9 home runs and also scored 50 runs. Braxton Ashcraft is the starting pitcher for the Pirates. His ERA stands at 2.62, and his WHIP is 1.19. Ashcraft has a record of 4 wins and 3 losses this season.

Final Betting Pick

The Pirates are on a four-game winning streak, including two wins against the Reds. This momentum makes their money line at +141 an appealing choice. Their recent road success, despite a challenging overall road record, shows they can perform well away from home.

The over/under prediction of under 8.0 is based on both teams having strong starting pitchers. Braxton Ashcraft has an ERA of 2.62, while Nick Lodolo has an ERA of 3.44. The previous games in this series have also been low-scoring, reinforcing the likelihood of another game with fewer runs.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.