Pittsburgh Pirates vs Cincinnati Reds MLB Betting Prediction

MLB Pittsburgh Pirates vs Cincinnati Reds Prediction 9/23

The Pittsburgh Pirates will play against the Cincinnati Reds on Tuesday, September 23, 2025, at 6:40 PM. The game will take place at Great American Ball Park in Cincinnati, OH. The weather forecast predicts a mild day with light rain and a light breeze. The Pirates have a record of 67-89, while the Reds stand at 80-76.

Pirates vs. Reds Betting Prediction

  • Money Line Prediction: Cincinnati Reds -157. The Reds have a strong home record of 44-34 and are on a five-game winning streak. With Brady Singer’s solid pitching, they are likely to continue their winning ways at home.
  • Over/Under Prediction: Under 8.5 (-111). Both teams have shown strong pitching, with the Reds allowing only 3.91 ERA and the Pirates at 3.82 ERA. This suggests a low-scoring game.

Team Trends

  • Pittsburgh Pirates have a road record of 23-52 this season.
  • Cincinnati Reds hold a home record of 44-34 this season.
  • The Reds are currently on a 5-game winning streak.
  • Pirates recently won two consecutive games against the Athletics.
  • The game will take place at Great American Ball Park with a forecast of light rain.

Pirates vs Reds Preview

The Pittsburgh Pirates will visit the Cincinnati Reds for a game at Great American Ball Park. The Pirates are currently 67-89 and are ranked fifth in their division. They have won their last two games but have struggled in their last ten, going 3-7. Johan Oviedo will start for the Pirates. He has a 3.52 ERA and a 1.24 WHIP with a 2-0 record this season.

The Cincinnati Reds, with a record of 80-76, are third in their division and have won their last five games. They have a 6-4 record in their last ten games. Brady Singer will be on the mound for the Reds. He has a 3.86 ERA, a 1.22 WHIP, and a 14-10 record. The game will be played on a mild day with light rain and a light breeze.

Reds’ Key Players and Pitching Preview

The Cincinnati Reds have some strong hitters on their team. Elly De La Cruz leads the team in runs with 100, ranking 10th in the league. Spencer Steer tops the team in home runs with 21, which places him 21st in the league. Brady Singer will be the starting pitcher for the Reds in this game. Singer has a record of 14 wins and 10 losses. His ERA is 3.86, and his WHIP is 1.22, making him a key player on the mound. Overall, the Reds rank 13th in team batting average at .245. Their on-base percentage is .314, and they have hit 161 home runs this season. The pitching staff has a team ERA of 3.91, ranking 13th in the league.

Pirates Prepare for the Game

Andrew McCutchen is the top hitter for the Pittsburgh Pirates. He has a batting average of .240 and has hit 13 home runs this season. McCutchen leads the team in runs with 50 and RBIs with 57. Spencer Horwitz and Jared Triolo also contribute to the Pirates’ offense. Horwitz has a .257 batting average and has hit 9 home runs. Triolo, playing 102 games, has a .233 average with 7 home runs. Johan Oviedo will pitch for the Pirates. He has a 2-0 record with an ERA of 3.52. His WHIP stands at 1.24, making him a solid choice on the mound.

Final Betting Pick

The Cincinnati Reds have been strong at home with a 44-34 record. They are on a five-game winning streak, which boosts their confidence. Brady Singer is set to pitch, and he has a solid 14-10 record with a 3.86 ERA. This makes the Reds a favorable pick for the money line at -157.

For the over/under, both teams have shown strong pitching this season. The Reds have an ERA of 3.91, while the Pirates have an ERA of 3.82. These numbers suggest a low-scoring game. The under 8.5 at -111 looks like a good choice, considering the pitching strengths of both teams.


All odds are courtesy of Action247 Sportsbook. Good luck!!


* All odds are provided by Action247 Sportsbook and all odds subject to change. **All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk. Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.